New study links obesity to the immune system

Dr Strange

This new study which includes scientists from Ireland shows a link between a certain immune cell disrupting the fat burning process and obesity:

http://www.rte.ie/news/2016/0901/813535-obesity/

Saipanne

It's only a coincidence that fat people love cake.

darkpagandeath

People with Genuine fat issues that's fine. but you will get #curvy jumping on this to say it's them not eating to much. Some have fat issues and cant loose weight but the majority are just fat.

The_Valeyard

Saipanne wrote: »

It's only a coincidence that fat people love cake.

I'm not fat or cuddly. But i do love cake. What Gene is responsibile for that? Tasty Gene. Nom nom nom.

Giacomo McGubbin

Calories taken in vs Calories expended. It's as simple as that.

Saipanne

The_Valeyard wrote: »

I'm not fat or cuddly. But i do love cake. What Gene is responsibile for that? Tasty Gene. Nom nom nom.

I love cake too, just not a whole one.

Dyr

Theres a link between the fridge and obesity

The_Valeyard

Saipanne wrote: »

I love cake too, just not a whole one.

Depends on the size!

_Brian

darkpagandeath wrote: »

People with Genuine fat issues that's fine. but you will get #curvy jumping on this to say it's them not eating to much. Some have fat issues and cant loose weight but the majority are just fat.

My wife is a nutritionist and says the actual number of obease people who get so through means other than poor lifestyle choices is minuscule, a fraction of a %.

The vast majority whether through phscyological or other reasons just live a poor lifestyle.

riffmongous

A lot of people not going to be happy with this

Seth Brundle

riffmongous wrote: »

A lot of people not going to be happy with this

Will they resort to comfort eating?

Winterlong

I am not fat and am always catching a cold. The study must be a pile of ****e.

Junkyard Tom

I'm overweight because I'm allergic to salad and exercise.

whiskeyman

Junkyard Tom wrote: »

I'm overweight because I'm allergic to salad and exercise.

Try this wonderful recipe for pizza salad

Dr Strange

You are all evil and horrible human beings

RTÉ explains it:

Traditionally weight gain and obesity have been seen by people as the result of bad diet and inadequate exercise.

But according to experts, the majority of people find it very difficult to lose weight once they gain it, because the causes of obesity are far more complex.

...

The findings of the research, published in the journal Cell Metabolism, have been successfully tested in patients attending the obesity clinic of Professor Donal O'Shea, Consultant Endocrinologist at St Vincent's University Hospital and the Conway Institute, University College Dublin.

"These findings represent a significant step forward in our understanding of why people often find it so hard to lose weight, despite their best efforts," he said.

"The findings should help break many of the stigmas associated with obesity, and most importantly, they could dramatically improve outcomes for patients.

...

"The findings should help break many of the stigmas associated with obesity, and most importantly, they could dramatically improve outcomes for patients.

Not in AH it won't.

Sod the science and the evidence and stuff, dem fatties be so lazy they let the wind blow their noses. Right?

Zxclnic

New study links obesity to the immune system.............
......and coincidentally we are pleased to announce this brand-new 'immune system/stay slim drug' costing €2,473.89 per packet of two tablets....
........because you're worth it!

wakka12

Maybe its harder for others to lose fat than some.
But if you consume less calories than you burn every day, even for just a little while. You will lose weight, theres just no two ways about it

Seth Brundle

wakka12 wrote: »

Maybe its harder for others to lose fat than some.
But if you consume less calories than you burn every day, even for just a little while. You will lose weight, theres just no two ways about it

Unless you're big boned or have a hormonal problem or its in your genes

andekwarhola

Glands, your honour.

Dyr

kbannon wrote: »

Unless you're big boned or have a hormonal problem or its in your genes

Did'nt see any fatties rolling around Ethiopia or Sudan going "I don't know what it is, I just can't shift the weight"

Put the f**king fork down.

andekwarhola

Bambi wrote: »

Did'nt see any fatties rolling around Ethiopia or Sudan going "I don't know what it is, I just can't shift the weight"

I'd hazard a guess that's down to malnourishment and starvation. Could be wrong.

PARlance

Dr Strange wrote: »

You are all evil and horrible human beings

RTÉ explains it:

I think you left out the most important part of the article.

"Ultimately, this research underlies the absolute importance of prevention of weight gain in the first place. This work should be used by policy makers to prioritise obesity prevention strategies, especially childhood obesity"

Dr Strange

PARlance wrote: »

I think you left out the most important part of the article.

"Ultimately, this research underlies the absolute importance of prevention of weight gain in the first place. This work should be used by policy makers to prioritise obesity prevention strategies, especially childhood obesity"

No, I just don't include full quotes. Everyone can read up on the full text and study (as you did). It's interesting though to see the attitude to a proper experimental study which lead to clinic-based observations and ended in a peer-reviewed international publication being simply dismissed.

I don't blame the vast majority of the populace not understanding the principles behind scientific research though. Critical evaluation of research projects is not necessarily part of the school curriculum. So it would be up to the researchers to communicate science in simple terms.

However, there will always be a core group that will not even consider the findings as it just doesn't fit with a previously formed opinion that is much easier to be bandied about than discussing all possibilities. Nobody has said that overeating is not a problem but that obesity is a complex problem just like any other physical and mental illness. No illness is just black and white.

Dyr

andekwarhola wrote: »

I'd hazard a guess that's down to malnourishment and starvation. Could be wrong.

Calories in, Baby.

the groutch

all studies like this do is give Big Pharma the ammo to market more placebos as a magic pill to burn fat.

Dr Strange

the groutch wrote: »

all studies like this do is give Big Pharma the ammo to market more placebos as a magic pill to burn fat.

Seriously? You accuse someone like Prof O'Shea of that? The mind boggles.

PARlance

I find it interesting that people focus on the problem as being the need to "cure" obesity rather than preventing it.

Dr Strange

PARlance wrote: »

I find it interesting that people focus on the problem as being the need to "cure" obesity rather than preventing it.

This is just one aspect of it. Prevention and cure go hand in hand. You have to have both at this stage as you have both types of people: possible future patient if it isn't prevented and already obese patients.

mikhail

Giacomo McGubbin wrote: »

Calories taken in vs Calories expended. It's as simple as that.

You should write this up and submit it to Nature. Science is in need of clear headed thinkers like you.

PARlance wrote: »

I find it interesting that people focus on the problem as being the need to "cure" obesity rather than preventing it.

The reported work is from a group that studies inflammation and the immune system, work that's really important in everything from arthritis to cancer.

I hope this is a wake-up to all those parents of fat children. You people are putting your children in serious danger, and the harm your feeding is causing them won't be undone with something as simple as joining an athletics club.

The W.H.O. has said that Ireland is at the forefront of a major obesity crisis. One in three young girls is overweight/obese, and so is one in five boys.

If we stick to the current trend, 90% of men will be obese/overweight by 2030, and 85% of women. This country needs an enormous serving of cop-the-fcuk-on.

Giacomo McGubbin

Giacomo McGubbin wrote: »

Calories taken in vs Calories expended. It's as simple as that.

Technically true from a physics point of view, but we are not orbs existing within a body. Different people have differing natural levels of willpower, differing highly complex psychological backstories explaining why they find it easier or harder than others not to overconsume high-calorie foods etc. Personal responsibility is something people need to *take upon themselves* (and something for which they should be admired if they do so) because the concept of absolute responsibility has no basis in reality, in spite of what ones control-hungry ego might want to believe. And I say this as someone lucky to be in good shape because I *happen to* have genetics that predispose me to find it easier than others to maintain a good weight and *also* happen to possess decent levels of willpower, lower subjective experience of satisfaction from food than I know others have (I get no enjoyment from ice cream, crisps, cake, biscuits among other foods) and the kind of stubborn, obsessive mind that facillitates losing weight and maintaining weight loss if I do happen to put on some weight. Other people have different innate personalities and natures to me and they can't just "will" themselves to be otherwise on command. Most peoples "understanding" of the concept of free will is still based in the 1st millenium BC.

Very few, because they didn't live in an environment conducive to the development of obesity, regardless of their innate natures .. obviously!

Zemazor

Zemazor wrote: »

Ok so the choices people make still determines if they become obese.

Obviously. I am arguing that nobody is ultimately responsbile for the activity of their brain, and hence their choices. It is not fair for a fit person to castigate an obese person for their being obese, since the fit person finds its easier to not be obese (either because they are genetically predisposed to not have a compulsion to overeat, or else they *are* genetically predisposed to have a compulsion to overeat *but* also a predisposed to have willpower enough to counteract this in the long run (although studies wil show the percentages of people who become obese and keep the weight off in the long run to be very small, so such people are probably quite rare)).

We have all been encultured from a young age to assume as based in reality the concept that each of us has enough "oomph" to bring about any conceivable state of affairs we desire "if we just try hard enough" ... in reality, our brain is a lump of meat with brillitant thoguh limited abilities. After exerting willpower for long periods of time, cognitive depletion sets in and a person reverts back to their "natural" behaviour habits.

Just like a dog can't will itself to talk like a human, so many obese individuals simply cannot will themselves to maintain a non-obese weight long term. That's my take on it anyway. And even *if* they try to out-willpower this, eventually they come to the end of their rope and their *definite* maximum willpower just isn't enough. And even if you've recently lost a few stone and kept it off, say for a year or two, and think what I've written is bollocks - come back in 10 years and see what way your maintainance has went!

Also, this thing about obesity levels increasing - in my observation there are way fewer obese people than 10 years ago. I find it hard to believe rates are not coming down.

Wigglepuppy

darkpagandeath wrote: »

People with Genuine fat issues that's fine. but you will get #curvy jumping on this to say it's them not eating to much. Some have fat issues and cant loose weight but the majority are just fat.

The only thing that causes people to be overweight is consuming more calories than they need. It is not possible to gain weight without excess calories, and these excess calories do not materialise through e.g. genetics, they are entirely due to excess food.

People have different body types, burn calories at a differing rate (not much though, usually), there are people with eating addictions (eating disorders do not just have to involve under-eating, they can involve over-eating too) and who struggle to control themselves when it comes to food, but there is one hundred per cent just one physical cause of being overweight.

uch

Saipanne wrote: »

It's only a coincidence that fat people love cake.

Hey, leave cake out of this you blaggard

uch

Wigglepuppy wrote: »

The only thing that causes people to be overweight is consuming more calories than they need. It is not possible to gain weight without excess calories, and these excess calories do not materialise through e.g. genetics, they are entirely due to excess food.

People have different body types, burn calories at a differing rate (not much though, usually), there are people with eating addictions (eating disorders do not just have to involve under-eating, they can involve over-eating too) and who struggle to control themselves when it comes to food, but there is one hundred per cent just one physical cause of being overweight.

You're wrong, I'm a big munter not because of what I eat but because I drink too much, your argument is flawed

Wigglepuppy

uch wrote: »

You're wrong, I'm a big munter not because of what I eat but because I drink too much, your argument is flawed

Ok calories meaning food AND drink.

uch

Wigglepuppy wrote: »

Ok calories meaning food AND drink.

Ah look I wasn't trying to be a prick, but theres a lot of misconceptions about weight, food and drink are the biggest ones, but lack of exercise is the biggest IMO, I'm a short arséd fat little bollix, but I swim regularly, play football once a week, and walk about 30 miles a week, I'm healthy as fúck, and have been told so by several doctors, you don't have to be like a butchers pencil to be fit and healthy

MAJJ

Candie wrote: »

Not in AH it won't.

Sod the science and the evidence and stuff, dem fatties be so lazy they let the wind blow their noses. Right?

The topic should be elsewhere on boards. Candie, you have a way with words and have read many of them and don't think I have responded to one yet but couldn't let this one past..... a laugh out loud classic, thank you.

Zemazor

Zemazor wrote: »

I would agree with this, there were more fat people in 2006 imo.

My instincts tell me that cultural forces and pressures with their origins in the rise of social media and internet are a big reason why. Along with it being the case that nowadays being massively successful in your life by the standards of the past is the new bar for "acceptable", that allows people to feel psychologically comfortable in themselves, so people try harder than before to not put on weight while young, or to lose it if they have put it on. Gym culture has balooned in the last decade. Everyone looks way, way better looking than 10 years ago. People take way more pride in their appearance. Personally, I much preferred the old way of things - much less shallow, pressurising, sterile. Everyone has access to the internet to read about nutrition, fitness etc. - how many people in 2000 were knowledgeable about what role each micronutrient played in the diet for example. How many people do you know who *haven't* joined the gym at some point in the last 5 years, people who in 2006 would have been predicted never to set foot in one? I would put money on it being the case that rates of obesity are way down on 10 years ago.

GerryDerpy

Cut your cake slice in half and you can eat twice as much!

I love a bit of cake!

uch

GerryDerpy wrote: »

Cut your cake slice in half and you can eat twice as much!

I love a bit of cake!

Hey, don't be takin my line

Wigglepuppy

A Tyrant Named Miltiades! wrote: »

I hope this is a wake-up to all those parents of fat children. You people are putting your children in serious danger, and the harm your feeding is causing them won't be undone with something as simple as joining an athletics club.

The W.H.O. has said that Ireland is at the forefront of a major obesity crisis. One in three young girls is overweight/obese, and so is one in five boys.

If we stick to the current trend, 90% of men will be obese/overweight by 2030, and 85% of women. This country needs an enormous serving of cop-the-fcuk-on.

I'm surprised at that though - the vast majority of children I see are not overweight. If anything I sit up and take notice when I see an overweight kid as i feel sorry for them.

endacl

Saipanne wrote: »

It's only a coincidence that fat people love cake.

You made tea come out my nose. Thanks.

:mad:

I've a good few overweight friends and thankfully they all know they're fat cause of their lifestyles. For me, once I put on an extra two kilos, which is usually during the summer, I just cut down on the calories and it goes away.

Maybe it's easy to do cause I know it works.

Wigglepuppy

Wigglepuppy wrote: »

I'm surprised at that though - the vast majority of children I see are not overweight.

I don't know why you're surprised, that's exactly what the statistics tell us.

22% of boys are overweight/obese, 78% are not
30% of girls are overweight/obese, 70% are not.

But according to the W.H.O., when you walk around Dublin or Cork or Limerick in 15 years time, the overwhelming majority of people, i.e. 85-90% of all people, will be overweight/obese. We're already over half-way there. Irish men are the fattest in Europe.