From the Irish Times on Monday, 19 Dec 2011.
DRUG REGULATORS have advised caution in the use of one of the Republic’s most widely used anti-nausea agents after the emergence of a possible link with sudden cardiac death. The warning is especially targeted at people aged over 60.
Domperidone, which is marketed here as Motilium and Domerid, is a long-established drug that is used to treat nausea and vomiting.
As well as having antiemetic properties, domperidone helps to propel food along the gut and is a proven treatment for upper abdominal discomfort and fullness.
Available over the counter as well as on prescription, the drug is especially popular at this time of year as an antidote to seasonal overeating.
In its latest drug safety bulletin, the Irish Medicines Board (IMB) warns doctors that two recent studies “have shown that domperidone may be associated with an increased risk of serious ventricular arrhythmias or sudden cardiac death”.