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JAMA report on the reliability of published medical studies

davros · 2005-07-24 21:21:50

An interesting study in the Journal of the American Medical Association looked at the incidence of studies published in major medical journals that were subsequently refuted. A good article on the report is here while the orginal abstract is here (full text requires a subscription). This quote sums it up: I'm thinking of…

24-07-2005 10:21PM

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davros

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An interesting study in the Journal of the American Medical Association looked at the incidence of studies published in major medical journals that were subsequently refuted.

A good article on the report is here while the orginal abstract is here (full text requires a subscription).

This quote sums it up:

According to Ioannidis, "five out of six non-randomized studies and nine out of 39 randomized studies were contradicted or found to have stronger effects compared with subsequent studies on the same topic." Smaller studies were more likely to be refuted than larger ones, and findings from non-randomized trials were often overturned by the results of a larger, randomized trial.

I'm thinking of the occasional published studies on alternative medicine in respected journals that get cited repeatedly thereafter as proof of efficacy.

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