Legality of restricted drugs with potential therapeutic benefit:

Primary focus from a neurological view point would be drugs implicating "emotional" affect.

Fascinating case report.

A member of a radical political group of sorts experiences dramatic emotional and thus cultural perspective shift following such drug intervention:

Unlocked:

https://sci-hub.hkvisa.net/https%3A//www.sciencedirect.com/science/article/abs/pii/S0006322321000858

sam t smith

Would the same experiment turn an ‘antifa’ goon into a neo-Nazi?

In other words, facilitation of cognitive (rationalization of oneself and ones environment, mediated in thought process) modification, following a monoamine booster intervention.

Most notably, cognitive modifications are sustained beyond "acute effects of the drug".

Historically psychedelics and dissociatives are used to induce the theorized "cognitive reset".

Paradoxically they dull cortical (executive and cognitive function) neural activity, where stimulant based compounds either raise or equalize cortical activity (again, mediating cognitive function).

I guess you could argue it's either a "push or pull" type of affect relative to one person versus the next.

Whether it's dulling or enhancing cortical neural activity, the end goal being to induce a perspective shift and thus facilitate neuro-plastic changes and modifications (cognitive evolution - demonstrated in that paper as directly influencing cultural/political beliefs and leanings);

Where cortical and thus cognitive "dampening" via psychedelics = suited to some neural-states (personality-types).

"Boosting" cortical and thus cognitive function = the necessary mediator in other personality types.

Given abuse potential, I understand the reluctance of clinicians and policy makers to endorse licencing of such drugs for these purposes but..... it's definitely worth keeping the conversation going;

No doubt.