If you have a new account but are having problems posting or verifying your account, please email us on [email protected] for help. Thanks :)
Private profiles - please note that profiles marked as private will soon be public. This will facilitate moderation so mods can view users' warning histories. All of your posts across the site will appear on your profile page (including PI, RI). Groups posts will remain private except to users who have access to the same Groups as you. Thread here
Some important site news, please read here. Thanks!

Protein sequencing

  • 21-05-2020 2:57pm
    Registered Users Posts: 6 ✭✭✭ cladonia

    Hi Guys,

    I am complete nube at genetics and bioinformatics.

    Can some one please tell me.... if we analyse and determine the protein sequence of an enzyme produced by a given strain, and we then use that to determine the gene sequence from the organism that produced it?

    I thought the mature peptide or amino acid sequence of the enzyme would be different to the amino acid sequence of the gene - or is that stupid?:confused:

    Thanks guys


  • Moderators, Science, Health & Environment Moderators Posts: 4,502 Mod ✭✭✭✭ Tree

    Many amino acids have more than one codon that codes for them (redundancy, woo!), so you can't properly predict a (D|R)NA sequence from an amino acid sequence. I mean, you could have a stab at it... but you'd also be missing any introns that might get excised too.

    A given (D|R)NA sequence will have a single amino acid string as its output (with appropriate intron handling, etc).