Dopamine NDRI'S medications for depression prescribed in Ireland?

edmethod

I starting taking L-Tyrosine (an amino acid precurser to dopamine) and I couldn't believe how well it worked, I felt really good again, got my libido back after about 10 years, self confidence restored and just went about life attaining my own happiness but I have seemed to have developed a tolerance since to the tyrosine so I'm back at square one again.

Can't quite believe it, I had a taste of freedom for a while and at the the time my only regret was where I could be in life if I was on the tyrosine years ago, I had ambition again, drive motivation etc.

Arranged an appointment with a public Pdoc, he was really bad, didn't seem to listen to anything I was saying, didn't even seem to care and this seems to be the experience Iv had with nearly every state employed pdoc Iv seen, I explained to him everything and the fact Iv had zero results with ssri's, I suffer from major seasonal depression and have had zero libido for 10 years, from everything Iv read NDRI's are used to treat these symptom's.
I don't want happy pill's, I just want to be able to feel good again, do I have to go private to see a decent psychiatrist that actually listens and be effective?, does anyone know which dopamine meds are available?

Cheer's.

Hersheys

I don't mean to come across as cunty but you say you don't want "happy pills" yet ask to be prescribed NDRI's, which are, in themselves, "happy pills".

I think your best bet would be to make an appointment with a GP that you have a good rapport with and explain your issue; NDRI's are only prescribed for a very limited range of psychiatric/behavioural disorders.

It's also important to have your medical condition recorded. A good GP will listen to your concerns and may suggest other non-Pharma solutions if that's the route you want to take, but no doctor, at least no good doctor, will prescribe NDRI's based on you taking L-tyrosine & requesting a medical equivalent. Aside from anything else I think depression is an off-label indication for NDRI's in Ireland.

Out of interest how much L-tyrosine were you taking on a daily basis?

edmethod

NDRI's like welbutrin are commonly prescribed in the U.S for depression, Iv read great success story's along with a few horror storys, I don't think been able to feel good and feeling happy for no reason other then a pill are the same thing and ssri's will not improve my already non existent libido.

500mg tyrosine once in the morning.

Hersheys

edmethod wrote: »

NDRI's like welbutrin are commonly prescribed in the U.S for depression, Iv read great success story's along with a few horror storys, I don't think been able to feel good and feeling happy for no reason other then a pill are the same thing and ssri's will not improve my already non existent libido.

500mg tyrosine once in the morning.

Welbutrin, Bupropion being the generic/active compound, is not on the market in Ireland. Anything that acts as an NDRI is not licensed for use as an antidepressant in Ireland (well any of the ones that I have checked in the last few hours). There are, however, certain SSRI's and MAOI's that do not impact libido, or other medication you can take that may boost your libido.

Just out of interest, where did you hear about tyrosine? And what made you decide on a dosage of 500 mg? Curiosity mainly but also I have done a lot of scientific research on amino acid metabolism in humans and different pathway activations as a result of amino acid metabolism. So I'm curious as to why you chose L-tyrosine, rather than the more commonly used phenylalanine? And what measures you put in place to stop the excess dopamine being converted to adrenaline?

And of course I'm interested in the placebo effect of L-tyrosine as it has been clinically shown to not exhibit any effect on dopamine levels at the levels you're consuming.

Have you ever spoken to a doctor, other than the public psychiatrist, about your SAD and what options are available to you medically if you don't want to further decrease your libido? Because that really is the best option.

edmethod

Hey, the tyrosine was recommended to me, I tried the phenylalanine after the tyrosine had worn off and experienced no effect, I took no measures to reduce what I think you meant was norepinephrine?, didn't know there was any steps that good be taken to reduce this, do you think it's the increase in norepinephrine that could have stopped the tyrosine working?, I'm gunna try and take a longer break from it this time and see if it works better when I start back on it.

Hersheys

The conversion of norepinephrine to adrenaline is more or less a given. Too much adrenaline in your body can be a bad thing, it can increase anxiety and may even increase symptoms of depression.

Seriously, go talk to your doctor or go privately to a psychiatrist. Tell them how important your libido is and how you don't want to take SSRI's. 500 mg of L-tyrosine is not a therapeutic dose. It will not benefit you. Only 1 amino acid has been shown to have an actual effect on depression symptoms (beyond the placebo effect, in clinical trials and derivatives of it are used in the pharma industry) and it's not L-tyrosine.

There are other treatments available for SAD. UV light boxes. Talk therapy. Non pharma based methods. Other natural compounds. But it is better for you to beat this in conjunction with a doctor as playing around with what are essentially mind altering compounds when you're not in the best mental state can be fatal.

noah45

Hersheys wrote: »

Welbutrin, Bupropion being the generic/active compound, is not on the market in Ireland. Anything that acts as an NDRI is not licensed for use as an antidepressant in Ireland (well any of the ones that I have checked in the last few hours)

I was prescribed bupropion (zyban)150mg for depression alongside effexor 300mg for depression about 3 years ago. Zyban is to help you stop smoking but an off licence use is depression. Effexor on its own wasn't helping meand bupropion did help. Took some time for any improvement but I'm doing fairly ok at the moment.

Hersheys

noah45 wrote: »

Hersheys wrote: »

Welbutrin, Bupropion being the generic/active compound, is not on the market in Ireland. Anything that acts as an NDRI is not licensed for use as an antidepressant in Ireland (well any of the ones that I have checked in the last few hours)

I was prescribed bupropion (zyban)150mg for depression alongside effexor 300mg for depression about 3 years ago. Zyban is to help you stop smoking but an off licence use is depression. Effexor on its own wasn't helping meand bupropion did help. Took some time for any improvement but I'm doing fairly ok at the moment.

My bad - didn't think it was on the market here. Knew it was an off label use so very few docs would prescribe it without another med. in your case Effexor.

edmethod

I really dont believe the tyrosine was placebo the first few weeks were very intense, I felt like I was on a pill that was a fraction of the drug from limitless and Iv read others using the same description, my cognitive functioning was highly increased, loads of energy, high libido all this lead to highly increased self confidence, it was pretty great.