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ageing of transplants

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  • 10-03-2012 7:09am
    #1
    lg123
    Registered Users Posts: 1,039 ✭✭✭


    i'm here watching the fountain of knowledge that is greys anatomy and some young guy is getting a penis transplant. i dont know if thats even possible or ever been done but that dosnt matter. as the guy in question is young my first thought was how would a transplant like this age?

    or for heart, kydney, etc, how do they age? for instance, if a 20 year old guy gets a heart from a 60 year old donor, would he have an 80 year old mans heart at 40?

    all the above is hypothetical....


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    #2
    Jimoslimos
    Registered Users Posts: 4,930 ✭✭✭Jimoslimos


    Actually the transplanted organ would technically only be a few years old since most cell types in the body renew themselves.


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    #3
    Improbable
    Registered Users Posts: 1,576 ✭✭✭Improbable


    Jimoslimos wrote: »
    Actually the transplanted organ would technically only be a few years old since most cell types in the body renew themselves.

    The problem is that they don't do it perfectly i.e. telomere shortening.


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    #4
    [Deleted User]
    Posts: 0 ✭ [Deleted User]


    Improbable wrote: »
    The problem is that they don't do it perfectly i.e. telomere shortening.

    Which is why cloning is also an issue


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    #5
    IrishKnight
    Registered Users Posts: 922 ✭✭✭IrishKnight


    Starla_o0 wrote: »
    Which is why cloning is also an issue

    Telomere shortening isn't the biggest issue with cloning, indeed some cases it was found that the telmeres were longer in the cloned animal than in the donor. The biggest issue is DNA methylation...

    But all of that is more of an aside...


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    #6
    Improbable
    Registered Users Posts: 1,576 ✭✭✭Improbable


    IrishKnight wrote: »
    Telomere shortening isn't the biggest issue with cloning, indeed some cases it was found that the telmeres were longer in the cloned animal than in the donor. The biggest issue is DNA methylation...

    But all of that is more of an aside...

    Interesting. I hadn't actually heard that before. Any links?


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