If you have a new account but are having problems posting or verifying your account, please email us on hello@boards.ie for help. Thanks :)

Hello all! Please ensure that you are posting a new thread or question in the appropriate forum. The Feedback forum is overwhelmed with questions that are having to be moved elsewhere. If you need help to verify your account contact hello@boards.ie

Hi there,
There is an issue with role permissions that is being worked on at the moment.
If you are having trouble with access or permissions on regional forums please post here to get access: https://www.boards.ie/discussion/2058365403/you-do-not-have-permission-for-that#latest

Stupid Question (Pharmacology)

PhysiologyRocks · 2010-05-08 00:02:51

Are any receptor antagonists endogenous?

08-05-2010 12:02AM

#1

PhysiologyRocks

Registered Users, Registered Users 2 Posts: 2,813 ✭✭✭

Join Date: May 2009

Posts: 2671

Are any receptor antagonists endogenous?

0

Comments

#2 08-05-2010 03:35AM

[Deleted User]
Posts: 8,647 ✭✭✭

Join Date: -

Posts: 8647

InterLeukin 1? It to do with fevers and bone degradation.

0
#3 08-05-2010 12:16PM

mardybumbum

Registered Users, Registered Users 2 Posts: 1,937 ✭✭✭

Join Date: June 2007

Posts: 1875

Christ, I actually cant think of any apart from IL - 1Ra.
Theres bound to be more surely.

Actually if you google "endogenous antagonist" quite a few come up that I have never heard of before.
An endogenous melanocortin antagonist?

0
#4 08-05-2010 10:18PM

Kurtosis

Registered Users, Registered Users 2 Posts: 2,881 ✭✭✭

Join Date: February 2006

Posts: 2477

One interesting (hypothesised) endogenous antagonist is Diazepam binding inhibitor (DBI), a peptide that is thought to bind the benzodiazepine site on the GABA A receptor and may actually be implicated in a decreased efficacy of diazepam at times of extreme stress due to displacing/preventing its binding.

0