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'Modestly' successful AIDs vaccine

  • 21-10-2009 12:04pm
    #1
    marco_polo
    Moderators, Science, Health & Environment Moderators Posts: 10,092 Mod ✭✭✭✭


    No harm in highlighting a bit of positive vaccine coverage for a change. A small step along what is still a very long road ahead but an encouraging signs nonetheless.

    http://www.newscientist.com/article/dn18011-first-hiv-vaccine-trial-success-confirmed.html

    The first HIV vaccine to be called a success has stood up to scrutiny after further analysis of the data was presented today in Paris, France.

    However, the new analysis also confirms that the optimistic claims, first made in September and viewed sceptically at the time, are indeed very modest.

    ......................

    The risks of infection in the vaccinated group were reduced by around 60 per cent within a year, but by 30 months after vaccination the protective effect was only 36 per cent. This resulted in a 31 per cent figure overall.

    "It looked like there's an early effect that wanes with time," said Berkley. "It may be that the vaccine generates only weak antibodies against HIV, and these are only effective early on."



Comments

  • #2
    tallaght01
    Closed Accounts Posts: 5,778 ✭✭✭tallaght01


    I don't know what to make of this. First we were told it was very significant, with a 30% risk reduction. Then we were told the results were a crock due to confounders and non statistically significant results. Now we're being told the results are encouraging again.

    SO everyone was waiting for them to present their results at this meeting in Paris, so some figures might get into the public domain. But I've seen nothing yet.

    Hoping for NEJM online express article sometime soon :P


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