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Vasoconstriction discussion

  • 02-08-2009 5:22pm
    #1
    Carsinian Thau
    Closed Accounts Posts: 2,054 ✭✭✭


    Subject to this: http://www.boards.ie/vbulletin/showpost.php?p=61380610&postcount=7

    I'd actually quite like to have one now!


    I know that the conditions that cause vasoconstriction and vasodilation are reversed in lungs compared to the rest of the body but I was just wondering what physiological processes (aside from nervous control, I can understand that I think) govern this?


Comments

  • #2
    Chunky Monkey
    Closed Accounts Posts: 923 ✭✭✭Chunky Monkey


    There's hormonal control as well (through hormonal feedback systems). Oh lord I need to revise. Okay from what I remember...there's the renin-angiotensin-aldosterone (RAA) system...angiotensinogen (protein) is produced in the liver. Renin (enzyme) converts this to angiotensin I which is converted by the angiotensin-converting enzyme (ACE) to Angiotensin II in the lungs.

    Angiotensin II causes aldosterone (hormone) release from the adrenal glands. This messes around with ions and water in the nephrons in the kidneys and thus increases blood pressure. Angiotensin II also acts directly on the artery walls causing vasoconstriction.

    Sorry that's a pretty poor reply, this is terrible I've forgotten already!

    This diagram from wikipedia might explain a little better...http://en.wikipedia.org/wiki/File:Renin-angiotensin-aldosterone_system.png


  • #3
    ZorbaTehZ
    Registered Users, Registered Users 2 Posts: 2,149 ✭✭✭ZorbaTehZ


    It's a terribly interesting subject actually, especially when you get into the tissue-specific factors. Jordan & Marshall's "Cardiovascular Regulation" is a good collection of some recent topics in it.


  • #4
    PhysiologyRocks
    Registered Users, Registered Users 2 Posts: 2,813 ✭✭✭PhysiologyRocks


    Anybody know much about vascular spasm? Can it be caused by an excess of general factors involved in vasoconstriction?


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