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Hypokalaemia

  • 29-04-2009 7:50pm
    #1
    Closed Accounts Posts: 174 ✭✭


    How do corticosteroids and gentamicin casue hypokalaemia?


Comments

  • Closed Accounts Posts: 61 ✭✭flerb22


    gentamicin is nephrotoxic, can mess up ionic balance


    corticoids act on the same receptors as aldosterone but with less efficacy...i think.
    though they def do cause hypokalaemia, its a cushingoid symptom.


    hopefully that makes a little sense


  • Registered Users, Registered Users 2 Posts: 3,461 ✭✭✭DrIndy


    to be more detailed - gentamycin can induce a renal tubular acidosis or a barrter-like syndrome rarely and cause a hypokalaemia.

    Corticosteroids have a direct action causing a cushinoid syndrome which induces aldosterone to lose potassium

    http://emedicine.medscape.com/article/242008-overview


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