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COVID-19: Vaccine and testing procedures Megathread Part 3 - Read OP

Beasty

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No anti-vax stuff in this thread - it's to discuss the various vaccines available and how they are getting rolled out, as well as testing procedures

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Sanjuro

Vaccination numbers for Wednesday 31st March-

14,796 first doses
9,434 second doses

24,230 total

Via HSE Covid dashboard

CIARAN_BOYLE

funnydoggy wrote: »

What's the story with AstraZeneca and the South African variant? Reading one or two articles from the past week saying the vaccine isn't doing great towards it. Am I reading the wrong articles?

There was a South African study that didn't look good but its a weak study with an insane confidence interval.

There hasn't been a reliable study yet. I am confident that it would have some benefit but I would not be suprolised to see recipients called for a booster at a later date.

timsey tiger

Sanjuro wrote: »

Vaccination numbers for Wednesday 31st March-

14,796 first doses
9,434 second doses

24,230 total

Via HSE Covid dashboard

~8% up on Wednesday last week, I was hoping for a more significant ramp-up.

irishlad.

timsey tiger wrote: »

~8% up on Wednesday last week, I was hoping for a more significant ramp-up.

Expected a little more myself too, but its still the highest Monday, Tuesday and Wednesday so far. Signs are good for a high number tomorrow.

Dose 1 & 2's moving along nicely in cohort 3

https://docs.google.com/spreadsheets/d/1cUZy6AMCwuA2zhtRuKK7cqMVgmhdDsGsZrFWJTkw9DY/edit#gid=1219026690

head82

Anyone else heard about this new variant.. "le variant breton"?
I only found out about it this morning so I may be just late to the party.

From an article in Forbes dated 17 March:

"A new variant of the novel coronavirus has been identified in the French region of Brittany. On Monday evening, the French Ministry of Health put out a statement that said the mutation was found by way of genomic sequencing in a cluster of infections in a hospital in the town of Lannion. Eight of 79 Covid-19 patients turned out to be carriers of the new variant, nicknamed “le variant breton.” Initially they tested negative with gold-standard PCR tests, despite presenting with typical symptoms of Covid-19. But later, coronavirus infection was confirmed with analysis of blood samples and tissue in the respiratory system. All 8 patients have since died".

Daniel2021

[Deleted User] wrote: »

My husband got an appointment for Tuesday in City Hall Cork ( cohort 4) the relief!

Any idea what vaccine he will be given, he just got a call, he didn't think to ask. It doesn't matter he is happy with either, I am just interested to know when he will be fully vaccinated.

Do you mind me asking how he was identified as part of cohort 4? Was it via his gp or a a hospital? Thanks

r93kaey5p2izun

Is the plan for everyone outside the priority groups (say 30s, 40s, healthy) to be done by GPs? What about someone with no GP? Will there be a mechanism for them to sign up somewhere else?

Sono Topolino

funnydoggy wrote: »

What's the story with AstraZeneca and the South African variant? Reading one or two articles from the past week saying the vaccine isn't doing great towards it. Am I reading the wrong articles?

It only protects against severe Covid-19 from SA variant.

The reason that the HSE is using AZ is twofold: 1) they spent a lot of money buying it and have committed themselves to it 2) it still provides some protection.

If you get the AZ jab, you will need to get revaccinated next year.

timsey tiger

Does anyone know what the story with Moderna is, re our roll out?

Our deliveries appear to be 40,800 to end of Feb. and 27,600 in mid march.

Seems to me that the 40,800 should be in arms by now 2 doses for 20,400 people, I'm not sure if there is an overfill gain for moderna aka pfizer and a further 13,800 first doses from the march delivery. But todays dashboard is saying only 33,738 doses of moderna administered.

I guess it could mean that only one dose from both delvieries has been used because the first lot came just before end of Feb. and it took some time to roll out, this would be near enough to the 33,738. 20,400 + 13,800 = 34,200.

ACitizenErased

Sono Topolino wrote: »

It only protects against severe Covid-19 from SA variant.

The reason that the HSE is using AZ is twofold: 1) they spent a lot of money buying it and have committed themselves to it 2) it still provides some protection.

If you get the AZ jab, you will need to get revaccinated next year.

Could ya not post bull****? Cheers

stephenjmcd

timsey tiger wrote: »

Does anyone know what the story with Moderna is, re our roll out?

Our deliveries appear to be 40,800 to end of Feb. and 27,600 in mid march.

Seems to me that the 40,800 should be in arms by now 2 doses for 20,400 people, I'm not sure if there is an overfill gain for moderna aka pfizer and a further 13,800 first doses from the march delivery. But todays dashboard is saying only 33,738 doses of moderna administered.

I guess it could mean that only one dose from both delvieries has been used because the first lot came just before end of Feb. and it took some time to roll out, this would be near enough to the 33,738. 20,400 + 13,800 = 34,200.

Numbers look right to me. 50% of each delivery are to be held back as per Moderna request

68,400 is 34,200 to be used and 33,738 used

funnydoggy

Thanks folks. Was genuinely curious, good bunch of people here

trellheim

Shot plot update one week on. Data correct as of Government website. Figures across both shots and all vaccine types . Data points are total number of shots into arms every day. Low points all Sundays

Sono Topolino

ACitizenErased wrote: »

Could ya not post bull****? Cheers

Where is the lie though?

Oh you don't like me calling into question the long term efficacy of a vaccine that is demonstrated to be less effective against a particularly virulent mutation of SARS-CoV-2 already present in Ireland? You don't like me pointing out that if you get this less efficacious vaccine, you will need to get revaccinated next year?

If can prove me wrong about this, please do so - but it is the general consensus among doctors that those getting AZ will need to get revaccinated next year, as mutations develop. Eventually the protection provided by Pfizer and Moderna will wear off too. The data suggests that they provide robust protection against all known variants and mutation. This will change in time.

That isn't BS or controversial - it's just how these things work, I'm afraid.

EDIT: I am not Antivaxx and if you are given the opportunity to take AZ, by all means take it. It's a luxury commodity at the moment and the benefits obviously outweigh the risk. And the fact that you will need to get revaccinated next year isn't a reason not to get vaccinated this year. Christ people, read what I am actually saying.

ACitizenErased

Sono Topolino wrote: »

Where is the lie though?

Oh you don't like me calling into question the long term efficacy of a vaccine that is demonstrated to be less effective against a particularly virulent mutation of SARS-CoV-2 already present in Ireland? You don't like me pointing out that if you get this less efficacious vaccine, you will need to get revaccinated next year?

If can prove me wrong about this, please do so - but it is the general consensus among doctors that those getting AZ will need to get revaccinated next year, as mutations develop. Eventually the protection provided by Pfizer and Moderna will wear off too. The data suggests that they provide robust protection against all known variants and mutation. This will change in time.

That isn't BS or controversial - it's just how these things work, I'm afraid.

Demonstrate it so? And don’t bother posting that nonsense SA trial with the humongous confidence interval

CIARAN_BOYLE

head82 wrote: »

Anyone else heard about this new variant.. "le variant breton"?
I only found out about it this morning so I may be just late to the party.

From an article in Forbes dated 17 March:

"A new variant of the novel coronavirus has been identified in the French region of Brittany. On Monday evening, the French Ministry of Health put out a statement that said the mutation was found by way of genomic sequencing in a cluster of infections in a hospital in the town of Lannion. Eight of 79 Covid-19 patients turned out to be carriers of the new variant, nicknamed “le variant breton.” Initially they tested negative with gold-standard PCR tests, despite presenting with typical symptoms of Covid-19. But later, coronavirus infection was confirmed with analysis of blood samples and tissue in the respiratory system. All 8 patients have since died".

There's limited information about it. There is a big lab report from French laboratories due about it on Monday according to one of the French news sources so we might have more information then.

Sono Topolino

ACitizenErased wrote: »

Demonstrate it so? And don’t bother posting that nonsense SA trial with the humongous confidence interval

I'm referring to the noted conspiracy theorists and purveyors of nonsense, the University of Minnesota Centre for Infectious Disease Research and Policy: https://www.cidrap.umn.edu/news-perspective/2021/03/astrazeneca-vaccine-doesnt-prevent-b1351-covid-early-trial

"AstraZeneca vaccine doesn't prevent B1351 COVID in early trial
Two doses of the AstraZeneca-Oxford University COVID-19 vaccine were ineffective against mild-to-moderate infections with the B1351 variant first identified in South Africa, according to a phase 1b-2 clinical trial published today in the New England Journal of Medicine."

The cheek of them quoting directly from a clinical trial! It goes on to say that second generation vaccines are already in development. The nerve!

Of course anyone who gets the AZ vaccine will not get revaccinated once a second generation vaccine against this virulent variant becomes available in large quantities - that would be completely illogical, wouldn't it? We would never do that.

political analyst

Was the process of manufacturing vaccines not explained to Frau von der Leyen?

https://www.theguardian.com/world/2021/jan/26/why-has-astrazeneca-cut-vaccines-to-eu-and-will-it-impact-uk-

Making vaccines is not like building houses, where you can add a few more bricks to a wall if it’s too short, they say. This is a biological process and it’s not possible to be certain how much vaccine is going to be made once production is under way. The yield varies.

In this case, there appears to have been a low yield from the cells dividing in the bioreactors in the Belgium plant. The same could happen in any of the other factories around the world making the Oxford/AstraZeneca vaccine, including the UK.

stephenjmcd

Sono Topolino wrote: »

I'm referring to the noted conspiracy theorists and purveyors of nonsense, the University of Minnesota Centre for Infectious Disease Research and Policy: https://www.cidrap.umn.edu/news-perspective/2021/03/astrazeneca-vaccine-doesnt-prevent-b1351-covid-early-trial

"AstraZeneca vaccine doesn't prevent B1351 COVID in early trial
Two doses of the AstraZeneca-Oxford University COVID-19 vaccine were ineffective against mild-to-moderate infections with the B1351 variant first identified in South Africa, according to a phase 1b-2 clinical trial published today in the New England Journal of Medicine."

The cheek of them quoting directly from a clinical trial! It goes on to say that second generation vaccines are already in development. The nerve!

Of course anyone who gets the AZ vaccine will not get revaccinated once a second generation vaccine against this virulent variant becomes available in large quantities - that would be completely illogical, wouldn't it? We would never do that.

The holes in that report have been pointed out by numerous posters here and online when it was originally published.

To name just a few,

1. Dosing interval not adhered to
2. Confidence intervals big enough to fit a jumbo jet through
3. Small sample set
4. Possible dodgy anti body tests (a recent revelation)

But yeah by all means continue to post it when it's been discussed numerous times and widely dismissed until an actual proper study is carried out. We're just going to go in circles

Sono Topolino

stephenjmcd wrote: »

The holes in that report have been pointed out by numerous posters here and online when it was originally published.

To name just a few,

1. Dosing interval not adhered to
2. Confidence intervals big enough to fit a jumbo jet through
3. Small sample set
4. Possible dodgy anti body tests (a recent revelation)

But yeah by all means continue to post it when it's been discussed numerous times and widely dismissed until an actual proper study is carried out. We're just going to go in circles

Who would win? Boards.ie users or the New England Journal of Medicine and the South African Government which has made the expensive decision to switch to the Johnson and Johnson vaccine....

Edit: your critiques aside, this study and paper has been peer reviewed and deemed sufficiently rigorous to be published. But sure, go ahead and diss it.

stephenjmcd

Sono Topolino wrote: »

Who would win? Boards.ie users or the New England Journal of Medicine and the South African Government which has made the expensive decision to switch to the Johnson and Johnson vaccine....

Your literally rehashing an argument that was had here weeks ago and tbh I'm not bothered entertaining you.

Quite easy to go off and find the study being disputed by many scientific sources, dig back through the thread and you'll find plenty of them linked.

JTMan

Pete_Cavan wrote: »

Not sure if it is more desirable to have them vaccined before the start of the new school year or not. Maybe the logistics of vaccinating the school kids would be easier when they are all together in school, in which case waiting until September would make sense.

Logistically, yeah, it would be easier to jab 12-15 year olds on their first day back. However, why wait until then and have people mixing without immunity. It makes more sense for the first dose to be given at least 3 weeks before the new school year starts.

Deeper Blue

Sono Topolino wrote: »

I'm referring to the noted conspiracy theorists and purveyors of nonsense, the University of Minnesota Centre for Infectious Disease Research and Policy: https://www.cidrap.umn.edu/news-perspective/2021/03/astrazeneca-vaccine-doesnt-prevent-b1351-covid-early-trial

"AstraZeneca vaccine doesn't prevent B1351 COVID in early trial
Two doses of the AstraZeneca-Oxford University COVID-19 vaccine were ineffective against mild-to-moderate infections with the B1351 variant first identified in South Africa, according to a phase 1b-2 clinical trial published today in the New England Journal of Medicine."

The cheek of them quoting directly from a clinical trial! It goes on to say that second generation vaccines are already in development. The nerve!

Of course anyone who gets the AZ vaccine will not get revaccinated once a second generation vaccine against this virulent variant becomes available in large quantities - that would be completely illogical, wouldn't it? We would never do that.

Would people ever stop posting that nonsense study. Sick of seeing it being used as some sort of "proof" that we're all doomed because of "de varientz"

JTMan

England seem to be not that far from herd immunity.

54.7% now have antibodies.

60% is considered the minimum level required.

funnydoggy

What have I started ðŸ˜‚

Leinster90

Has anyone seen any clear information on when the 65-70 age bracket will begin to be vaccinated, and a reasonable prediction of how long it will take?

Russman

Leinster90 wrote: »

Has anyone seen any clear information on when the 65-70 age bracket will begin to be vaccinated, and a reasonable prediction of how long it will take?

HSE website says they (Cohorts 5 & 6) can register online from “before 19th April”, so presumably they’ll start around then.

timsey tiger

stephenjmcd wrote: »

Numbers look right to me. 50% of each delivery are to be held back as per Moderna request

68,400 is 34,200 to be used and 33,738 used

Yes, but held back until when? 40,800 was delivered before end of february shouldn't those second shots be in arms by now?

Icantthinkof1

Sono Topolino wrote: »

If you get the AZ jab, you will need to get revaccinated next year.

Where was that confirmed?

[Deleted User]

Could you get an Astra now (fully protected June/July) and when supplies are plentiful say in September/October could you get Pfzier for extra assurance?

"The best vaccine you can get is the earliest one"

Would you be allowed medically to take multiple vaccines at a point in the future?