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COVID-19: Vaccine and testing procedures Megathread Part 3 - Read OP

Beasty

Thread 1
Thread 2

No anti-vax stuff in this thread - it's to discuss the various vaccines available and how they are getting rolled out, as well as testing procedures

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Chawosfski

Leftwaffe wrote: »

Genuine question here. Could we buy more vaccines outside the EU vaccine program? How difficult would this be and what vaccines are available? If it’s possible, why aren’t we doing it?

We've setup a task force

Or are setting it up

Leftwaffe

Genuine question here. Could we buy more vaccines outside the EU vaccine program? How difficult would this be and what vaccines are available? If it’s possible, why aren’t we doing it?

is_that_so

average_runner wrote: »

Wouldn't you want to give it to.the people that paid for it first. EU is way too slow and will prolong lockdown well into the summer.

Thank god the outdoor season is here, numbers dropping and kids having fun playing outside.

The EU aim is to have a summer, tourism accounts for 10% of GDP and some countries genuinely afford another lost summer economically, hence the enthusiasm to work on vaccine passports. As for AZ, annoying one customer over another is really not good business, especially one that can block your supply chain.

is_that_so

Wolf359f wrote: »

It will be interesting to know where Canada is getting their J&J supply from, as they approved before the EMA, if it's shipping from the EU and it's no stopped, it could mean J&J have a decent supply ready for us.
Then again, they could pull an AZ and say they will deliver and then ship it all to Canada and then say opps, I did it again!

J&J manufacture vaccines anyway, they know what they are doing. AZ by the looks of things do not with all the wide boy juggling of supplies that is going on.

average_runner

Wolf359f wrote: »

It will be interesting to know where Canada is getting their J&J supply from, as they approved before the EMA, if it's shipping from the EU and it's no stopped, it could mean J&J have a decent supply ready for us.
Then again, they could pull an AZ and say they will deliver and then ship it all to Canada and then say opps, I did it again!

Wouldn't you want to give it to.the people that paid for it first. EU is way too slow and will prolong lockdown well into the summer.

Thank god the outdoor season is here, numbers dropping and kids having fun playing outside.

Tippbhoy1

UDAWINNER wrote: »

Why was there a shortage of supplies for the Over 85s as they all say it was AZ fault, but this cohort would be getting Pfizer or Moderna. Am I missing something?

Shortfall in cohort 2, HCW getting AZ, made back up from supplies originally planned for cohort 3.

UDAWINNER

Why was there a shortage of supplies for the Over 85s as they all say it was AZ fault, but this cohort would be getting Pfizer or Moderna. Am I missing something?

Melanchthon

astrofool wrote: »

There's a study done on similar coronavirus (i.e. colds) that the reason they're so non-lethal (and they do kill, just in very low numbers) is their endemic nature, so our immune response is built up throughout life (think how diseases we brought to other countries killed so many at first).

Now, with SARS-COV2, a significant portion of the world is being vaccinated, it doesn't mutate as often as the flu, and it's mutations are limited to a few key areas (so far anyway, but other mutations look less beneficial), meaning, if it has a low level of mutation, but fast enough to keep spreading, it could become endemic, but we get a sniffle and move on, or it could go like smallpox/polio etc. and be eliminated entirely.

From a human perspective, attacking the virus and limiting it's effects on people is a function of a relatively short period of time (months to years), rather than an impossibility, it might be over after the first vaccine has been deployed effectively, or it might take a few updated vaccines to finish it off (all just speculation right now).

True but wouldn't the fact it wouldnt that not be a factor for the next day year or two.
Secondly if the virus is only seriously dangerous to a small minority it won't impact the selection pressure, basically like the way scarlet fever or similar became less dangerous.

Wolf359f

Stark wrote: »

Last forecast I saw was for 200,000 doses in April (and same for May, June).

It will be interesting to know where Canada is getting their J&J supply from, as they approved before the EMA, if it's shipping from the EU and it's no stopped, it could mean J&J have a decent supply ready for us.
Then again, they could pull an AZ and say they will deliver and then ship it all to Canada and then say opps, I did it again!

astrofool

Leftwaffe wrote: »

I’m gonna go with not enough and not as many as projected.

Shortfall of 75,000 by AZ in the last 2 weeks (on their already reduced supply), they promise they'll have it made back up by the end of March, everyone sceptical.

Leftwaffe

Klonker wrote: »

Just the next time restrictions may change is early April which will be looked at in late late March. So say by end of March how many doses and how many people could we expect vaccinated?

I’m gonna go with not enough and not as many as projected.

astrofool

Klonker wrote: »

Just the next time restrictions may change is early April which will be looked at in late late March. So say by end of March how many doses and how many people could we expect vaccinated?

We're looking at 650,000-ish, supplies permitting, probably about 250k fully dosed.

astrofool

There's a study done on similar coronavirus (i.e. colds) that the reason they're so non-lethal (and they do kill, just in very low numbers) is their endemic nature, so our immune response is built up throughout life (think how diseases we brought to other countries killed so many at first).

Now, with SARS-COV2, a significant portion of the world is being vaccinated, it doesn't mutate as often as the flu, and it's mutations are limited to a few key areas (so far anyway, but other mutations look less beneficial), meaning, if it has a low level of mutation, but fast enough to keep spreading, it could become endemic, but we get a sniffle and move on, or it could go like smallpox/polio etc. and be eliminated entirely.

From a human perspective, attacking the virus and limiting it's effects on people is a function of a relatively short period of time (months to years), rather than an impossibility, it might be over after the first vaccine has been deployed effectively, or it might take a few updated vaccines to finish it off (all just speculation right now).

Klonker

Just the next time restrictions may change is early April which will be looked at in late late March. So say by end of March how many doses and how many people could we expect vaccinated?

Melanchthon

Here's a question that I don't think has been asked in the thread so far, I've forgotten an awful lot of my Biology though so maybe its simple enough

Also not trying to be one of the "varients are going to kill us all" people RTE type people.

Ok
So we know some of the variants seem to evade the antibody response to a varying degree. Call it Varient X

Its very very likely that the T cell response for vaccinated people will be more effective so severe illness will be avoid, however T cell response is laggy isn't it, so your going to end up with a transmission window?

If there is a vaccinated population that where the varient X is introduced, could a situation occur where the varient spreads like a "normal" cold e.g the vast majority of the population with a normal immune response just gets very mildly sick.
However those that are immune compromised end up severely sick?

I fully expect that even if that occurs we would unlock as the flu kills a bunch every few years anyway but curious if my reasoning is off in someway?

Water John

Stark wrote: »

Last forecast I saw was for 200,000 doses in April (and same for May, June).

You mean per week? Sorry I se you meant J & J.

Stark

pc7 wrote: »

Do we know how soon and much we will get for April?

Last forecast I saw was for 200,000 doses in April (and same for May, June).

afatbollix

To go back to testing:

I had my first at home antibody test yesterday,

(I had it done via blood test 2 months ago and had no antibodies)

I had to use one of those things they use to test for diabetes to get a bit of blood out of my finger and fill a vial. Took about 20 minutes and 2 fingers but they have the blood and it was sent overnight to the lab. I await the results. Wife took one look at the kit and said feck off so need to convince her its worth it for science :pac:

afatbollix

ACitizenErased wrote: »

The Brits have found the elusive Brazilian variant person

Found this gas, The person never filled out the right info when get they got the test and seemingly had it down to 350 houses in an area and went knocking on doors. :pac:

Just noticed that UK is testing close to a million a day. (0.5% are positive)

pc7

is_that_so wrote: »

Should be next Thursday for the EMA.

Do we know how soon and much we will get for April?

CIARAN_BOYLE

timsey tiger wrote: »

Has AZ been confirmed against SA variant. It would be a relief if SA variant is not an issue, I haven't heard anything since SA survey on young people with the large confidence interval.

Someone from the WHO spoke to Philipino news sources yesterday saying that reduced efficacy isn't a disaster and that reduced efficacy is the worst the az vaccine would ahe and that that isn't a problem.

No new studies.

is_that_so

Frank Bullitt wrote: »

J&J given the green light here in Canada, nice bit of news to end the week.

Should be next Thursday for the EMA.

xboxseries

timsey tiger wrote: »

Has AZ been confirmed against SA variant. It would be a relief if SA variant is not an issue, I haven't heard anything since SA survey on young people with the large confidence interval.

I wouldn't know Timsey, most of my reading is daily mail

From protecting against severe infection I read it has, but I just read that, agree would be good to know

xboxseries

Call me Al wrote: »

I think you've answered your own question there...

"AS LONG AS HE ISOLATED why the concern?"

They don't know if he has or not..

We know the vaccine's are effective so why the concern?

It's only one person.

Frank Bullitt

J&J given the green light here in Canada, nice bit of news to end the week.

ACitizenErased

brickster69 wrote: »

Germany urging people to take whatever potential protection they’re offered.

https://apnews.com/article/europe-emmanuel-macron-coronavirus-pandemic-france-berlin-cd9bc5d52877ef6d1a9b2dc427ac5a17

Anyone who refuses a specific brand of vaccine is a complete idiot

brickster69

Germany urging people to take whatever potential protection they’re offered.

https://apnews.com/article/europe-emmanuel-macron-coronavirus-pandemic-france-berlin-cd9bc5d52877ef6d1a9b2dc427ac5a17

Chawosfski

xboxseries wrote: »

Still don't get why the crazy man hunt for him? Most data says no variant escapes any vaccine, as long as he isolated why the concern?

Window Dressing

timsey tiger

xboxseries wrote: »

Still don't get why the crazy man hunt for him? Most data says no variant escapes any vaccine, as long as he isolated why the concern?

Has AZ been confirmed against SA variant. It would be a relief if SA variant is not an issue, I haven't heard anything since SA survey on young people with the large confidence interval.

Call me Al

xboxseries wrote: »

Still don't get why the crazy man hunt for him? Most data says no variant escapes any vaccine, as long as he isolated why the concern?

I think you've answered your own question there...

"AS LONG AS HE ISOLATED why the concern?"

They don't know if he has or not..