is_that_so wrote: » The EU is a bigger entity than both combined and not a single country. It also follows what the EMA says and applications for approval have stalled the process here. The US should have able to do what they are now promising, an inept Trump stopped that from happening.
greenheep wrote: » They managed to plan for that under the Trump days, hard to not feel like Europe dropped the ball. Europe should be on a par with the US and UK
Addressing Variants of Concern: On February 24, Moderna announced that it completed manufacturing of clinical trial material for its variant-specific vaccine candidate, mRNA-1273.351, against the SARS-CoV-2 variant known as B.1.351 first identified in the Republic of South Africa and has shipped doses to the NIH for a Phase 1 clinical trial that will be led and funded by the NIH’s NIAID. The Company also provided an update on its strategy for addressing SARS-CoV-2 variants of concern. Publication of Note: Letter to the editor in the New England Journal of Medicine published February 17, 2021, showed vaccination with the Moderna COVID-19 Vaccine produced neutralizing titers against all key emerging variants tested, including B.1.1.7 and B.1.351, first identified in the UK and Republic of South Africa, respectively. The study showed no significant impact on neutralizing titers against the B.1.1.7 variant relative to prior variants. A six-fold reduction in neutralizing titers was observed with the B.1.351 variant relative to prior variants.
2021 Financial Considerations Advance Purchase Agreements (APAs): Already signed APAs for scheduled delivery in 2021, reflecting a total of $18.4 billion in anticipated product sales. Additional discussions ongoing with several governments relating to APAs for scheduled deliveries in 2021 and 2022. Moderna responded to a tender to UNICEF to supply COVAX in 2021 and 2022 and discussions are ongoing with COVAX/UNICEF.
hmmm wrote: » https://twitter.com/POTUS/status/1366863233538228233
marno21 wrote: » Great news in that they will have surplus available which helps the worldwide pressure on demand. If the US can start supplying Canada in June if frees up supply constraints in Europe. Pfizer can supply from Kalamazoo rather than using Puurs for example.
titan18 wrote: » I'm still worried they're going to be taking J &J supply from us.
Danzy wrote: » When the current procurement program doesn't take things serious, countries will have to walk from it and get the results. Good to see this, gives us all more chances.
is_that_so wrote: » . At the very heart of this is vaccine nationalism and annoyance at the EU.
odyssey06 wrote: » From RTE - note that Denmark also seem to be looking for any spare vaccines from Israel: Austria has broken ranks with the European Union saying it would work together with Israel and Denmark to produce second-generation vaccines against mutations of the coronavirus. Chancellor Sebastian Kurz said Austria and Denmark, as members of the First Mover Group founded by him, would work with Israel on vaccine production against mutations of the coronavirus and jointly research treatment options. The announcement is a rebuke to the EU's joint vaccine procurement programme for member states which has been criticised for being too slow to agree deals with manufacturers.https://www.rte.ie/news/coronavirus/2021/0302/1200326-coronavirus-global/
Miike wrote: » Which conspiracy theories?
ninebeanrows wrote: » It will be amazing if the conspiracy theories around variants can be debunked in the coming weeks. It could really be possible to have a decent summer if we can get hard facts to say current vaccines work to virtually eliminate hospitalization and death in all variants of the disease.
Micky 32 wrote: » https://twitter.com/laoneill111/status/1366785207777517585?s=21
trellheim wrote: » Roisin is correct - we are miles off planned deliveries - I pointed this out earlier. it should have been 624,000 by 28 Feb delivered. Moderna and AZ numbers seem way way off the pace. There is no public information on this.
is_that_so wrote: » Well, they are supposed to have data this month.
eoinbn wrote: » June at the earliest. Their CEO is hoping for approval in June. Curevac won't be a factor this time around.
is_that_so wrote: » Well, they have a deal with Bayer to help up capacity. It was always at least Q2 anyway so April/May would be my guess. 405m on order for the EU.
Stark wrote: » Yeah I'm more curious as to if everything goes well with trials and approvals, how soon can doses actually start arriving.
is_that_so wrote: » There is no data on Curevac yet, should be this month and the EMA are doing a rolling review of it. That will make it faster but still 2 weeks+. J&J will be nearly a month on 11 March.
f 500,000 administered by Sun 7th, that comes to 64,005 for Sun 28th-Sun 7th. Seems low, even allowing for AZ 25,000 shortfall.
Stark wrote: » There was meant to be an accelerated process for variant boosters anyway. Will Curevac be able to deliver if approval comes more quickly? I haven't been able to find any information on their manufacturing process.
