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COVID-19: Vaccine and testing procedures Megathread Part 3 - Read OP

Beasty

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No anti-vax stuff in this thread - it's to discuss the various vaccines available and how they are getting rolled out, as well as testing procedures

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timsey tiger

Chris_5339762 wrote: »

Bound to happen given just how tricky this one is to store. Not good, but at least it is happening rarely.

Yea, re-reporting of a story from last month that was widely reported at the time. Unfortunately, it now appears that the vaccines would have fine.

JacksonHeightsOwn

is_that_so wrote: »

It's barely out of its trials and unapproved by the EMA. It hasn't submitted an application to the EMA yet although a rolling review may start soon. We follow the EMA as do the vast majority of EU members.

**** the ema, I'm not some anti EU man by the way, but they've dragged their heels on the vaccines, we all know that. If we had politicians with any civic pride they'd move heaven and earth to get vaccines here, h hi any means necessary.

brickster69

The Czech's to approve Sputnik

https://www.rt.com/news/516788-czech-sputnik-coronavirus-request/

Happydays2020

ddarcy wrote: »

With the US approving the Johnson and Johnson vaccination, we sound probably in March see it approved here as well.

Also interesting that my parents in the US have been told that they are moving to only one vaccination for Pfizer/ Moderna as this is good enough (still 80%+ efficacy) and the Phase IV information is supporting it. So they’ll get it next week and won’t need a second dose. They’re based in California and my aunt in Massachusetts has been told the same so it all seems to be heading this way, along with the UK, so we could shortly be seeing this as the official guidelines worldwide. I’d say by April the official dosing guidelines will be changed, if the information coming back remains the same.

That’s really interesting. Certainly will speed things along.

conor_mc

[Deleted User] wrote: »

It was Slovakia. And did nothing to interrupt transmission with surged after the national test campaign

I get your point, but was that a different outcome to PCR-tested countries that saw surges too?

The positive outcome was that it identified and interrupted 47,000 otherwise invisible chains of transmission, at that point in time.

I’m not advocating the same once-off approach per se, but there is an argument that as a complementary tactic, the widespread use of rapid antigen testing would help.

timsey tiger

chrisbonnie wrote: »

If only we had a pro active government.

Sputnik is a very good vaccine by all accounts

What is the availability of the Sputnik vaccine and what portion of the Russian pop. has already been vaccinated? Come back when the answers of both of these questions is high, until then ...

CIARAN_BOYLE

conor_mc wrote: »

I get your point, but was that a different outcome to PCR-tested countries that saw surges too?

The positive outcome was that it identified and interrupted 47,000 otherwise invisible chains of transmission, at that point in time.

I’m not advocating the same once-off approach per se, but there is an argument that as a complementary tactic, the widespread use of rapid antigen testing would help.

I've long felt that it should be used in healthcare settings and to test casual contacts.

I understand why they aren't used (false negative rate sufficiently high that there would be an increased level of risky behaviour with the belief, oh its OK I tested negative).

Goldengirl

Happydays2020 wrote: »

That’s really interesting. Certainly will speed things along.

Healthcare workers including myself , who have or may have had the infection previously have been reporting a greater reaction to the second dose of Pfizer .
I reported this here a few weeks ago.
Might mean that your body is reacting to that second dose strongly because it doesn't actually need it ?
I would not be surprised if the second dose was deemed unnecessary for those who have already tested positive in the future , but that is my non expert opinion

Melanchthon

Anybody have any good articles about the US emergency Johnson and Johnson approval.

Not saying it's the wrong move but it seems a funny one considering there seems to be good data now that Astra Zeneca is effective whereas the headline efficiency rate of J and J doesn't seem that high, and yes I am aware of the fact that it's basically really hospitalisation that matters as a metric so no need to repeat that point.

Basically I understand the rapid approval but I don't understand reasoning behind this not applying to other vaccines in US.

Deeper Blue

Melanchthon wrote: »

Anybody have any good articles about the US emergency Johnson and Johnson approval.

Not saying it's the wrong move but it seems a funny one considering there seems to be good data now that Astra Zeneca is effective whereas the headline efficiency rate of J and J doesn't seem that high, and yes I am aware of the fact that it's basically really hospitalisation that matters as a metric so no need to repeat that point.

Basically I understand the rapid approval but I don't understand reasoning behind this not applying to other vaccines in US.

Off the top of my head they wanted trial data in a US setting before signing off on AZ

is_that_so

Chris_5339762 wrote: »

Bound to happen given just how tricky this one is to store. Not good, but at least it is happening rarely.

Yeah, unfortunate now with the quantities but back in January almost a case for criminal charges.

Van.Bosch

chrisbonnie wrote: »

If only we had a pro active government.

Sputnik is a very good vaccine by all accounts

If it is a very good vaccine with proper testing and data to back it up, why have the Russians not asked for approval in any major market?

is_that_so

Van.Bosch wrote: »

If it is a very good vaccine with proper testing and data to back it up, why have the Russians not asked for approval in any major market?

They did or they thought they had but uploaded it to the wrong server! It'll come but probably not for a while.

Van.Bosch

is_that_so wrote: »

They did or they thought they had but uploaded it to the wrong server! It'll come but probably not for a while.

Yeah, like how believable is that?

“We have no application received for Sputnik”
“ we applied a few days ago”
“ looks like you uploaded incorrectly”
“Okay, we’ll reapply in a few weeks”

is_that_so

Van.Bosch wrote: »

Yeah, like how believable is that?

“We have no application received for Sputnik”
“ we applied a few days ago”
“ looks like you uploaded incorrectly”
“Okay, we’ll reapply in a few weeks”

The assertion is that they followed a now defunct process! EMA are talking to them and they should get a rolling review underway in the next while.

ddarcy

Melanchthon wrote: »

Anybody have any good articles about the US emergency Johnson and Johnson approval.

Not saying it's the wrong move but it seems a funny one considering there seems to be good data now that Astra Zeneca is effective whereas the headline efficiency rate of J and J doesn't seem that high, and yes I am aware of the fact that it's basically really hospitalisation that matters as a metric so no need to repeat that point.

Basically I understand the rapid approval but I don't understand reasoning behind this not applying to other vaccines in US.

[url] https://www.fda.gov/news-events/press-announcements/fda-issues-emergency-use-authorization-third-covid-19-vaccine[/url]

67% effective. Now before anyone complains, most flu vaccines are in the 50, low 60 % area.

Personally I think it so become an annual vaccination, so this is really good on that front. Pfizer and Modena should also be looking for full authorisation soon as well. Especially with 2+ months of more data.

bodhrandude

Where are we at in the vaccination queue here as I haven't a notion.

is_that_so

bodhrandude wrote: »

Where are we at in the vaccination queue here as I haven't a notion.

First and second shots for care homes and HCWs, first shots for over 80s.

ninebeanrows

On 30 April, HCW, 70+ & Medically vulnerable should be fully inoculated?

Van.Bosch

ninebeanrows wrote: »

On 30 April, HCW, 70+ & Medically vulnerable should be fully inoculated?

No - over 70s won’t all have second dose until mid May.

is_that_so

ninebeanrows wrote: »

On 30 April, HCW, 70+ & Medically vulnerable should be fully inoculated?

HCWs yeah but maybe well into May for over 70s and others, as they won't start for a few weeks anyway.

ninebeanrows

How long does immunity take after the one shot J&J? 3 weeks?

ninebeanrows

ninebeanrows wrote: »

How long does immunity take after the one shot J&J? 3 weeks?

28 days apparently, throw a load of J&J into people late March and we'll have them covered by end of April.

IRISHSPORTSGUY

https://www.bbc.com/news/world-us-canada-56226979

The European Medicines Agency could approve the drug for the EU in early March, with a speedy rollout to follow, French Industry Minister Agnès Pannier-Runacher said on Sunday.

Now that is important. It seems the production problems in the US may not necessarily extend to Europe.

JTMan

brickster69 wrote: »

The Czech's to approve Sputnik

https://www.rt.com/news/516788-czech-sputnik-coronavirus-request/

Not only that, as the FT are reporting here:
- Czech Republic have reached an agreement with Israel to obtain vaccines.
- Czech Republic have reached an agreement with the German state of Saxony to obtain vaccines. (I guess unused Oxford AZ vaccines).

Czech Republic are thinking outside of the EU supply box. I like it.

Are Ireland speaking to Israel? Saxony? US? etc about excess supply?

Ireland should copy the Czech Republic approach and get vaccines from countries with excess supply. I appreciate that we will have floods of vaccines by June but every sooner vaccine matters with getting us back to normal.

Cushtie

If the Germans are as reported sitting on 1.5 Million doeses for AZ that they can't administer for whatever reason, not giving it to over 65's., The population don't want it etc. Would it not make sense to have these redirected to other EU countries that would take them. Ie Us. Or am I missing something?

is_that_so

IRISHSPORTSGUY wrote: »

https://www.bbc.com/news/world-us-canada-56226979

Now that is important. It seems the production problems in the US may not necessarily extend to Europe.

Well, the EMA approval is expected to be 11 March anyway with deliveries planned from April.

josip

Caquas wrote: »

As you know it was Embraer’s chart that had its figures wrong, showing the Lithuanian figure for Ireland. And, as I said. that didn’t change my key point - there were no grounds for calling our vaccine rollout “exceptionally good”

At least we seem to have gone beyond the premature self-congratulations here and the “how many times must I tell you” or “ignore him” nonsense.

I never claimed to have all the answers but I don’t think the British would accept your explanations for their success. And Embraer’s chart did have an important message if s/he wasn’t so complacent. Some of the largest EU countries are not administering the AstraZeneca vaccine efficiently. Why can’t we get their stocks?
Europe’s AstraZeneca stockpile mounts as citizens snub jab https://on.ft.com/3ksLM9K
And just to be clear, I’d be delighted and impressed if we achieve the 82% target set by the Taoiseach by the end of June. Hell, I’d be impressed if it’s only 81.7% on 1 July. :cool:

The chart wasn't wrong, you were.

Micky 32

Government thinking of considering vaccine green cards :

https://www.irishexaminer.com/news/arid-40235168.html

titan18

IRISHSPORTSGUY wrote: »

https://www.bbc.com/news/world-us-canada-56226979

Now that is important. It seems the production problems in the US may not necessarily extend to Europe.

Wasn't there something about EU doses having to be shipped to the US for fill and finish. At which point, I'm pretty sure US will take them if they're not getting theirs.