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COVID-19: Vaccine/antidote and testing procedures Megathread [Mod Warning - Post #1]

Masala

Today being Paddy Day 2020... when do you think we will have a ‘flu jab’ / pill / syrup that we can take to make us immune/ les likely to catch this 19 virus?.

Mod: The purpose of this thread is baked into the title - COVID-19: Vaccine/antidote and testing procedures - it's not a platform to push an anti vaccination agenda. If posters wish to discuss the perceived cons of vaccinations, or push various theories regarding 'the agenda' (whatever that is supposed to mean), open a thread elsewhere on it.

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joseywhales

I am a bit concerned by the uptake, in light of reading this:

https://www.cnbc.com/2020/11/23/covid-vaccine-cdc-should-warn-people-the-side-effects-from-shots-wont-be-walk-in-the-park-.html

The pfizer and presumably moderna vaccine will be taxing on the body for a day or two, hopefully not enough to put people off.

JTMan

FT reports on UK vaccination planning here (paywall):

- Vaccinations could begin on 1 December.
- NHS works to get the first vaccinations.
- BT and Virgin Media installing broadband on 47 vaccination sites.
- Sites include Cheltenham Racecourse, the showgrounds in Truro in Cornwall, St Helens rugby league stadium, a retail unit in Stratford’s Westfield shopping centre in east London and a crypt underneath Blackburn Cathedral.
- The UK government is also planning to open vaccination centres within days in community, health and conference centres and museums across the country.

odyssey06

joseywhales wrote: »

I am a bit concerned by the uptake, in light of reading this:
https://www.cnbc.com/2020/11/23/covid-vaccine-cdc-should-warn-people-the-side-effects-from-shots-wont-be-walk-in-the-park-.html
The pfizer and presumably moderna vaccine will be taxing on the body for a day or two, hopefully not enough to put people off.

Might complicate rollout to frontline professionals though... would need to be staggered.

stephenjmcd

joseywhales wrote: »

I am a bit concerned by the uptake, in light of reading this:

https://www.cnbc.com/2020/11/23/covid-vaccine-cdc-should-warn-people-the-side-effects-from-shots-wont-be-walk-in-the-park-.html

The pfizer and presumably moderna vaccine will be taxing on the body for a day or two, hopefully not enough to put people off.

So potentially the same things your warned about every time you get a vaccine. Nothing new there that wasn't already known.

In the Pfizer trial it was around 2&3% of participants had either a headache or fatigue, not huge numbers.

Sure even getting the flu vaccine a few weeks ago I was told keep some paracetamol nearby just incase of headache and you might feel a bit crap, same as every year.

ShineOn7

JTMan wrote: »

FT reports on UK vaccination planning here (paywall):

- Vaccinations could begin on 1 December.
- NHS works to get the first vaccinations.
- BT and Virgin Media installing broadband on 47 vaccination sites.
- Sites include Cheltenham Racecourse, the showgrounds in Truro in Cornwall, St Helens rugby league stadium, a retail unit in Stratford’s Westfield shopping centre in east London and a crypt underneath Blackburn Cathedral.
- The UK government is also planning to open vaccination centres within days in community, health and conference centres and museums across the country.

That looks very well organised and planned so far

If Tony and that shambles of a gangster Paul Reid don't give us something similar tomorrow they'll be completely ignored by more and more of the population when they ask us to "keep the course there now"

manniot2

ShineOn7 wrote: »

That looks very well organised and planned so far

If Tony and that shambles of a gangster Paul Reid don't give us something similar tomorrow they'll be completely ignored by more and more of the population when they ask us to "keep the course there now"

A relative worked for Reid years ago in eircom. “Wouldn’t manage a sh1t in a toilet” is how he put it.

ShineOn7

joseywhales wrote: »

The pfizer and presumably moderna vaccine will be taxing on the body for a day or two, hopefully not enough to put people off.

Even a round of travel vaccines can knock you sideways for 48 hours, it's happened to me in the past with shots

Just watch the Anti Vax loons morph these very normal side effects into something out of a David Icke video though. They're almost literally brain dead

There's a year ahead of blocking/muting/un-friending more people on social media in the next 12 months than the last 10 years in total

timsey tiger

ShineOn7 wrote: »

Even a round of travel vaccines can knock you sideways for 48 hours, it's happened to me in the past with shots

Just watch the Anti Vax loons morph these very normal side effects into something out of a David Icke video though. They're almost literally brain dead

There's a year ahead of blocking/muting/un-friending more people on social media in the next 12 months than the last 10 years in total

The vaccine gave me covid I tell ya. :rolleyes:

D.Q

JTMan wrote: »

FT reports on UK vaccination planning here (paywall):

- Sites include Cheltenham Racecourse.

Back to the scene of the crime.

ShineOn7

timsey tiger wrote: »

The vaccine gave me covid I tell ya. :rolleyes:

Lol, we'll definitely get a few of those

Polar101

leahyl wrote: »

Is there going to be a longer wait in Ireland to get the vaccine? I don't understand why we haven't heard about a solid plan for vaccinating yet? I was really hopeful that we would be back to normality more or less by May at the latest.....you have the UK and the US saying how they'll have everyone vaccinated by April....but we haven't heard anything here....it's just worrying I really don't think I can do anymore than 3 or 4 months!!

It's going to be a bit longer, first a vaccine or vaccines need to be approved. After they know which vaccines can be used, then they can proceed with the vaccinations. It could still be by May, though - things look to be moving quite fast.

I wouldn't be looking to the UK or the US as an example on how to handle the pandemic. There's no point giving definite dates at this stage yet.

Voltex

stephenjmcd wrote: »

So potentially the same things your warned about every time you get a vaccine. Nothing new there that wasn't already known.

In the Pfizer trial it was around 2&3% of participants had either a headache or fatigue, not huge numbers.

Sure even getting the flu vaccine a few weeks ago I was told keep some paracetamol nearby just incase of headache and you might feel a bit crap, same as every year.

Its funny....when we bring our kids to get their 6 in 1 or MMR we're forewarned to dose them up on Calpol, as they may feel unwell or run a slight temperature....and yet this doesnt even phase us!

Stark

I remember any vaccine I've gotten, I've always been told to hang around for 15 mins afterwards just in case of a reaction.

Symptoms like headache and fever are a standard part of the immune response, it just means the vaccine is working.

MadYaker

JTMan wrote: »

FT reports on UK vaccination planning here (paywall):

- Vaccinations could begin on 1 December.
- NHS works to get the first vaccinations.
- BT and Virgin Media installing broadband on 47 vaccination sites.
- Sites include Cheltenham Racecourse, the showgrounds in Truro in Cornwall, St Helens rugby league stadium, a retail unit in Stratford’s Westfield shopping centre in east London and a crypt underneath Blackburn Cathedral.
- The UK government is also planning to open vaccination centres within days in community, health and conference centres and museums across the country.

They’re pandemic response so far has been a shambles, particularly the test and trace system and I doubt the rollout of the vaccine will be any different. Looks great on paper though.

[Deleted User]

MadYaker wrote: »

They’re pandemic response so far has been a shambles, particularly the test and trace system and I doubt the rollout of the vaccine will be any different. Looks great on paper though.

Seeing as we have zero information on anything the HSE has done, it is impossible to make a comparison.

mandrake04

Aegir wrote: »

Seeing as we have zero information on anything the HSE has done, it is impossible to make a comparison.

Antigen tests have been available since June, they are not perfect but they do have useful applications and are used in some Euro-overlord countries yet still not approved nor rolled out in Ireland.

Do expect vaccines to be any different?

Charles Babbage

There seems to be some disquiet over the AstraZenica vaccine trials, especially the discovery that a half dose first works best, especially as this was not intended. The data they have published seems unclear, for instance whether the half dose people had the same age mix as those in the regular trial. So there could be delay in approval of this vaccine as more trials might be required.

The EU has ordered 140m shots of the Moderna virus, so that should suffice for about one sixth of the Irish population.

Stark

Oxford/Astrazenaca vaccine might not be looking so good after all:

After Admitting Mistake, AstraZeneca Faces Difficult Questions About Its Vaccine https://nyti.ms/2J7csOY

tobefrank321

Hmmzis wrote: »

There is no mixing required for these vaccines as far as I'm aware of. Would you have a link to where it said that it needs mixing?

Sure.

https://news.sky.com/story/covid-19-vaccines-how-do-the-moderna-and-pfizer-coronavirus-jab-candidates-compare-12134062

During shipment and storage, the Pfizer vaccine must be kept at around -70C (-100F) to maintain optimal efficacy and it also has to be mixed with another liquid before it can be administered.

Admittedly information is sketchy in this story but I do recall a mention in some news story about the vaccine not being as straightforward to administer as traditional ones.

stephenjmcd

tobefrank321 wrote: »

Sure.

https://news.sky.com/story/covid-19-vaccines-how-do-the-moderna-and-pfizer-coronavirus-jab-candidates-compare-12134062

Admittedly information is sketchy in this story but I do recall a mention in some news story about the vaccine not being as straightforward to administer as traditional ones.

Only seems to be sky carrying that from what I can see. Didn't and haven't seen any mention of it in anything released by Pfizer nor any other sources.

Likewise no mention that I can find of it being any more difficult to administer than a normal vaccine. Open to correction with a source but couldn't find anything there when I looked.

The main concern around Pfizer is the storage concerns that have been raised alright but they don't look to be as big an issue as might have been thought.

Deeper Blue

Stark wrote: »

Oxford/Astrazenaca vaccine might not be looking so good after all:

After Admitting Mistake, AstraZeneca Faces Difficult Questions About Its Vaccine https://nyti.ms/2J7csOY

From what I can see the only quote in that article is from a guy working for a bank?

nommm

https://www.wired.com/story/the-astrazeneca-covid-vaccine-data-isnt-up-to-snuff/
Another good article here on the problems with the AstraZeneca announcement on Monday. Hopefully they can clear the issues raised up but at the moment it does look like a degree of cherrypicking has gone on with their data. Nowhere near as robust a study as Pfizer. They seem to have messed up their clinical trial design.

tobefrank321

Stark wrote: »

Oxford/Astrazenaca vaccine might not be looking so good after all:

After Admitting Mistake, AstraZeneca Faces Difficult Questions About Its Vaccine https://nyti.ms/2J7csOY

Interesting article. The successful lower dose/higher dose combination was only tested on under 55s and so its efficacy for the elderly is unclear. They'd have to run a new trial for that.

The obvious takeaway is the AZ vaccine would be ideal for the non vulnerable general public, but there's really no information as yet to suggest high efficacy for the elderly.

Pfizer and Moderna vaccines for the elderly, AZ for the young, or something like that.

Polar101

tobefrank321 wrote: »

The obvious takeaway is the AZ vaccine would be ideal for the non vulnerable general public, but there's really no information as yet to suggest high efficacy for the elderly.

Okay, but is there any information that suggest the opposite might be true, lower efficacy for the elderly/vulnerable people.

stephenjmcd

Polar101 wrote: »

Okay, but is there any information that suggest the opposite might be true, lower efficacy for the elderly/vulnerable people.

Its all ifs and buts, we (the public) see very limited data firstly, regulators will get everything before its made public.

Until they make a judgement its all speculation, we no idea whats in their submission nor does anyone writing an opinion piece

funnydoggy

Are the vaccine byyyyys meeting today?

hmmm

tobefrank321 wrote: »

The obvious takeaway is the AZ vaccine would be ideal for the non vulnerable general public, but there's really no information as yet to suggest high efficacy for the elderly.

Pfizer and Moderna vaccines for the elderly, AZ for the young, or something like that.

Yes. There's too much noise around AZ at the moment and the wood is being missed from the trees. Worst case scenario the trial was 70% effective with no severe Covid cases in the vaccinated group - those are still great results. Even better if they can move it up towards the 90% in time by running a bigger trial of the half/full dosing, but with the Moderna & Pfizer vaccines being redirected towards the highly vulnerable it should be good enough. We still have J&J and Novavax to come.

Irish Stones

JTMan wrote: »

FT reports on UK vaccination planning here (paywall):

- Vaccinations could begin on 1 December.

I wonder why the vaccination plans aren't starting the same day across Europe.
Over here the vaccinations should begin end of January, and it seems it will be mandatory to everyone.

Russman

Irish Stones wrote: »

I wonder why the vaccination plans aren't starting the same day across Europe.
Over here the vaccinations should begin end of January, and it seems it will be mandatory to everyone.

I though there's a document where the EU state that a vaccine will be available to all member states simultaneously. Its the only thing that makes sense if they want to avoid a free for all.

UK obviously free to do their own thing.

Russman

hmmm wrote: »

Yes. There's too much noise around AZ at the moment and the wood is being missed from the trees. Worst case scenario the trial was 70% effective with no severe Covid cases in the vaccinated group - those are still great results. Even better if they can move it up towards the 90% in time by running a bigger trial of the half/full dosing, but with the Moderna & Pfizer vaccines being redirected towards the highly vulnerable it should be good enough. We still have J&J and Novavax to come.

Is there any indication when these might have data ?