paw patrol wrote: » personal autonomy is overridden cos the stranger may get sick . If legally enforced that is tyranny. I'd consider the point is this was ebola-esque but it is not ...
hmmm wrote: » Another interesting vaccine candidate, but at a much earlier stage than the ones we've been discussing so far. What's interesting about this one is that it is showing good results, and uses the same processes as the Flu vaccine for manufacture - so could have large-scale manufacturing relatively quickly.https://www.biorxiv.org/content/10.1101/2020.07.26.221861v1.full.pdf "The NDV vector vaccine against SARS-CoV-2 described in this study has advantages similar to those of 48 other viral vector vaccines. But the NDV vector can be amplified in embryonated chicken eggs, which 49 allows for high yields and low costs per dose. Also, the NDV vector is not a human pathogen, therefore 50 the delivery of the foreign antigen would not be compromised by any pre-existing immunity in humans. 51 Finally, NDV has a very good safety record in humans, as it has been used in many oncolytic virus trials. 52 This study provides an important option for a cost-effective SARS-CoV-2 vaccine."
polesheep wrote: » They're not normally done simultaneously because each procedure informs the next. But look, this is a good thread and I wouldn't like to derail it. Here's hoping we get an effective and safe vaccine as soon as possible.
astrofool wrote: » Each procedure informing the next is used to decrease the costs of the process, especially if there is a lack of urgency, what they are doing now consumes more resources (as they basically have to verify every possible outcome from previous stage at the same time).
DesignerDublin wrote: » Fever is a common symptom but it's not always there and seems to happen later when people are already sick. Still, keeping track of temperature to try and pick up fever as early as possible is better than nothing I guess? Are many workplaces doing this? I'm not back in the office yet but I don't think this is planned for us.
Next, they looked at blood samples from 23 people who’d survived SARS. Their studies showed that those individuals still had lasting memory T cells today, 17 years after the outbreak. Those memory T cells, acquired in response to SARS-CoV-1, also recognized parts of SARS-CoV-2. Finally, Bertoletti’s team looked for such T cells in blood samples from 37 healthy individuals with no history of either COVID-19 or SARS. To their surprise, more than half had T cells that recognize one or more of the SARS-CoV-2 proteins under study here. It’s still not clear if this acquired immunity stems from previous infection with coronaviruses that cause the common cold or perhaps from exposure to other as-yet unknown coronaviruses.
irishgeo wrote: » Hopefully more than one vaccine is approved and this will reduce the time needed to roll it out. Might stop these anti vaccine idiots spouting rubbish that's it's for control of your mind. If there are multiple ones available from different companies with different methods of fighting it should stop the nonsense.
ACitizenErased wrote: » The Russian vaccine produced by the Gamaleya Institute is being approved within the next 2 weeks. Somehow I don't think there'll be a large take-up.https://edition.cnn.com/2020/07/28/europe/russia-coronavirus-vaccine-approval-intl/index.html
What Username Guidelines wrote: » The only hope I'm holding onto is that the internet has just amplified the noise from anti-vaxxers and that their numbers are smaller than appear. I know it's not a direct comparison, but even with the tracing app, I saw a lot of concern within the bubble of social media that no one would download it, yet it got to 1.4 million downloads very quickly. Hoping the vast majority will accept and take the vaccine. My daughter will probably not be able to get it so I am biased in hoping many will. As said above though, plenty will 'get away' with not getting it and rely on others for immunity, just like plenty have been living their lives like nothing is happening and they'll get away with that too "sure it was nothing to worry about, I was fine and I never followed guidelines.
hmmm wrote: » That's just it. Multiple phases are being run in parallel, and governments/CEPI are subsidising the costs (spending billions). I wish I could find it again, but one of the news sites had an online tool which showed the typical phases of vaccine development, and also showed how combining phases could drastically reduce the total time required without changing the length of any phase or compromising on safety. Starting work on manufacturing and scaling up before the trials were complete shaved years alone off the typical time required.
XPrize has launched a contest to develop new and improved testing methods for COVID-19.
hmmm wrote: » Russia has a lot of expertise in this area. Phase 1 and 2 trials can happen quickly. I'd say they are simply including high-risk populations (e.g. ICU staff) in what is a phase 3 trial, and calling it emergency approval. If I was a doctor on the frontlines, I'd probably be happy to take a jab at that point. If there's long-term implications of a vaccine, which is unlikely but possible, it's probably less of a risk than the immediate risk of getting the virus.
FutureTeashock wrote: » From what I've read, approximately 66% will take the rushed vaccine.
Gael23 wrote: » I’d take the Oxford one but not this one in Russia
FutureTeashock wrote: » I wouldn't take any of them, not if you put a gun to my head.
Marty Bird wrote: » Was this it ?https://news.sky.com/story/coronavirus-tracking-every-global-effort-to-find-a-covid-19-vaccine-12030675
El Sueño wrote: » Just in case we'd forgotten that you told us yesterday?