Possible spoilers further down, but not really spoilers, as it all happens in the 1st episode.http://www.imdb.com/title/tt3230454/
THE LAST MAN ON EARTH is a new single-camera comedy about the life and adventures of the last man on earth. PHIL MILLER (Forte) was once just an average guy who loved his family and hated his job at the bank - now he's humanity's last hope. Will he ever find another person alive on the planet? Would hoping that she is a female be asking too much?
The first bit was kinda funny, meeting the woman was kinda funny, but unless he kills her shortly, I can't see myself watching much more of it.
Also, the "nagging wife" thing has been done before. Can't see it lasting unless a 3rd wheel is introduced.