Covid 19 Part XXII-30,360 in ROI(1,781 deaths) 8,035 in NI (568 deaths)(10/09)Read OP

Sweet.Science · 10-09-2020 09:20AM

Wanderer78 wrote: »

will they be?

Yes. Phase 3 trials finish at the end of this month . Their findings will then go to regulators to approve or not.

Production already started on these vaccines months ago. So they will be ready for distribution

drunkmonkey · 10-09-2020 09:20AM

Pat Kenny and Luke O'Neill talking about BCG again, plenty of trials going on, can you request it from your doctor, we've 2 in the house haven't had it as it was scrapped.

Wanderer78 · 10-09-2020 09:22AM

Sweet.Science wrote: »

Yes. Phase 3 trials finish at the end of this month . Their findings will then go to regulators to approve or not.

Production already started on these vaccines months ago. So they will be ready for distribution

interesting, im still not convinced they ll be available this year, but hopefully so

podgeandrodge · 10-09-2020 09:30AM

is_that_so wrote: »

It depends on the type of test used. We know about this and as mentioned earlier on the thread it was highlighted internationally as an issue as early as April. De Gascun has drawn attention to the possibility of it more than once.

Sure, but the poster was treated like they were talking about 5g.

Edit:

mandrake04 wrote: »

So about the tongue in cheek, it just when Plantor quote 90% are not infected made me laugh so much.

Sure you cycle enough times you can detect RNA in the air, the question is not that virus can be detected but the viral load which is determined by the CT. (Cycle Threshold).

Gotcha. But it was NYTIMES quoting 90% in fairness!

Multipass · 10-09-2020 09:31AM

drunkmonkey wrote: »

Pat Kenny and Luke O'Neill talking about BCG again, plenty of trials going on, can you request it from your doctor, we've 2 in the house haven't had it as it was scrapped.

No, I’ve been looking into this as I missed the BCG. I was out of school the day the class had it, and my parents never bothered. There has been a shortage of the vaccine for years, and it doesn’t seem to be available in Ireland for any price.

DangerScouse · 10-09-2020 09:36AM

drunkmonkey wrote: »

Pat Kenny and Luke O'Neill talking about BCG again, plenty of trials going on, can you request it from your doctor, we've 2 in the house haven't had it as it was scrapped.

I had the BCG as did my wife and we both still caught the virus.

drunkmonkey · 10-09-2020 09:36AM

Multipass wrote: »

No, I’ve been looking into this as I missed the BCG. I was out of school the day the class had it, and my parents never bothered. There has been a shortage of the vaccine for years, and it doesn’t seem to be available in Ireland for any price.

There's plenty of evidence emerging it's effectiveness in lessening symptoms, the WHO are against it though, https://www.timesofisrael.com/century-old-vaccine-limits-covid-spread-so-bring-it-back-say-israeli-experts/
We probably should bring it back sooner rather than later.

Boggles · 10-09-2020 09:37AM

Sweet.Science wrote: »

Yes. Phase 3 trials finish at the end of this month .

No they won't.

End of next month is best case scenario on the leading candidates.

The trials hinge on numerous key data points, one of the primary ones being enough of the placebo volunteers get infected, if they don't the trial may have to start again.

Also if a vaccine does manage to get emergency use clearance, it can be pulled or paused as fast if it appears to be not safe or effective.

drunkmonkey · 10-09-2020 09:37AM

DangerScouse wrote: »

I had the BCG as did my wife and we both still caught the virus.

Nobody saving you won't get it but it won't be severe, how sick were the pair of you and did you pass it on to many?

NegativeCreep · 10-09-2020 09:39AM

Sweet.Science wrote: »

Yes. Phase 3 trials finish at the end of this month . Their findings will then go to regulators to approve or not.

Production already started on these vaccines months ago. So they will be ready for distribution

Do you think the regulators will just flick through the documents and sign on the dotted line in a day? It’ll take months to review the data. Then you have to come up with a process to manufacture the vaccine large scale and then actually manufacture enough of it for nearly every western country. No chance of a vaccine this side of Christmas.

DangerScouse · 10-09-2020 09:41AM

Sweet.Science wrote: »

Yes. Phase 3 trials finish at the end of this month . Their findings will then go to regulators to approve or not.

Production already started on these vaccines months ago. So they will be ready for distribution

Will be a miracle if we see a vaccine before the end of this year. Most likely it will be end of summer 2021 before widespread use is approved and only then if we are very lucky.

stephenjmcd · 10-09-2020 09:45AM

NegativeCreep wrote: »

Do you think the regulators will just flick through the documents and sign on the dotted line in a day? It’ll take months to review the data. Then you have to come up with a process to manufacture the vaccine large scale and then actually manufacture enough of it for nearly every western country. No chance of a vaccine this side of Christmas.

The approval process is being expedited for covid vaccines. Regulators are already involved and getting data as the trialls progress instead of getting it all at the end.

Manufacturing of multiple vaccine have already commenced.

It won't take months for approval. Pfizer expected to submit last trial data to regulator's by end of October and expect 100m doses to be delivered by end of 2020 with continued delivery throughout 2021 to just over 1.3 billion doses the current estimate.

TonyMaloney · 10-09-2020 09:46AM

alentejo wrote: »

I suspect this Irish wave will start to subside in October and continue to mid December.

It will then re-emerge in January & Feb which could be quite bad and tapper off as we get to Spring.

hmmm so opening schools, colleges and pubs is going to have a positive effect on the infection rate?

Fantastic! Tell us how

Martina1991 · 10-09-2020 09:48AM

podgeandrodge wrote: »

So are they saying that with the increased testing over last couple of months that we could be catching thousands of people that were asymptomatic a few months ago - is it possible that we are measuring a problem that doesn't really exist bar clearly new cases? Can they (or are they) measure the amount of virus in these PCR tests and see how many daily cases have significant amounts of virus?

Comparing our positivity rates to anywhere in the US, or anywhere else in the world is pointless if they are using different methods and platforms. They are not comparable.

It is statistically far more likely to get a false negative result than a false positive, due to sample collection. PCR amplification occurs many times to ensure that if any SARS-COV-2 viral material is present, then it can be detected. There isn't a way of determining how infectious a person is based on their test. The test will only determine how much viral material was on the actual swab.

If someone who tests positive is symptomatic or a close contact of someone who is symptomatic then they are likely actively infected. If someone tests positive and is asymptomatic then it is hard to determine at what stage of infection they are. So why risk it. Isolate for 14 days. Why run the risk of infecting someone just because you think you're not infectious.
These types of articles sound like another way to play down the seriousness or infectiousness of the virus.

stephenjmcd · 10-09-2020 09:48AM

DangerScouse wrote: »

Will be a miracle if we see a vaccine before the end of this year. Most likely it will be end of summer 2021 before widespread use is approved and only then if we are very lucky.

Theres a big difference between saying before we see a vaccine and widespread use.

As I said in a previous post Pfizer expect approval and delivery of initial vaccine by year end. This is only 1 vaccine. Many others with quite promising results in trials so far.

Widespread use yes during 2021.

There is much discussion and some excellent papers to read on the vaccine thread. Only yesterday Pfizer gave their latest update along with securing a deal with the EU commission.

NegativeCreep · 10-09-2020 09:48AM

stephenjmcd wrote: »

The approval process is being expedited for covid vaccines. Regulators are already involved and getting data as the trialls progress instead of getting it all at the end.

Manufacturing of multiple vaccine have already commenced.

It won't take months for approval. Pfizer expected to submit last trial data to regulator's by end of October and expect 100m doses to be delivered by end of 2020 with continued delivery throughout 2021 to just over 1.3 billion doses the current estimate.

I’ll eat my hat if it happens but I can’t see it

Sweet.Science · 10-09-2020 09:49AM

DangerScouse wrote: »

Will be a miracle if we see a vaccine before the end of this year. Most likely it will be end of summer 2021 before widespread use is approved and only then if we are very lucky.

Not a hope . Nov/Dec 2020

drunkmonkey · 10-09-2020 09:51AM

Sweet.Science wrote: »

Not a hope . Nov/Dec 2020

9 of the biggest pharmaceutical ceo's said it won't be this side of the US elections.

stephenjmcd · 10-09-2020 09:52AM

NegativeCreep wrote: »

I’ll eat my hat if it happens but I can’t see it

Pfizer seemed quite confident yesterday. Supply chains activated within the EU.

Data also looks quite good

Widdensushi · 10-09-2020 09:52AM

Pitch n Putt wrote: »

One swallow never made a summer

13 k a day unsustainable

Unable to meet demand now so meat factory testing paused.

The very places that have contributed to the new spikes.

Blame the community as the spread and specifically house gatherings.

Shouldn’t be declaring something that you can’t deliver on

Paul Reid should have known better.

And people still hanging on every word these people say.

They haven’t a clue just winging it as months and months pass by.

Surely the meat factories have a higher level of immunity now that will limit any spread from them. Need to be thinking where the virus is going, not where it has been, schools are where any excess capacity should be used, starting with the teachers.

munchkin_utd · 10-09-2020 09:53AM

stephenjmcd wrote: »

Pfizer seemed quite confident yesterday. Supply chains activated within the EU.

Data also looks quite good

yea, because these vaccines will need to be transported when frozen. The 2 vaccines I read about required -20 or -70 degrees storage along the entire supply chain, so you cant just pop it in a dhl or ups package and post it to the doctor.

stephenjmcd · 10-09-2020 09:55AM

munchkin_utd wrote: »

yea, because these vaccines will need to be transported when frozen. The 2 vaccines I read about required -20 or -70 degrees storage along the entire supply chain, so you cant just pop it in a dhl or ups package and post it to the doctor.

And you don't think that its currently being worked on ?

As Pfizer said yesterday, supply chains and logistics for Europe are activated.

Honestly read up on the announcements and trial data. The vaccine picture isn't as bleak as some want to believe

Dressoutlet · 10-09-2020 09:55AM

is_that_so wrote: »

And not that you're not doing it, stay home!

Thank you, as soon as I developed the weird taste I decided I wasn't leaving the house. I also found out last night I'm a close contact due to a now positive friend. Due to symptoms my Dr referred me for testing before contact tracing has called me even.

NegativeCreep · 10-09-2020 09:55AM

stephenjmcd wrote: »

Pfizer seemed quite confident yesterday. Supply chains activated within the EU.

Data also looks quite good

I bet their share price went up when they were positive about it too

10-09-2020 09:56AM

Boggles wrote: »

No they aren't.

71,910 in the last 7 days.

Combining the 13k daily test data and the 70k weekly indicates is peaks and troughs in testing demand that are causing delays, not single day demand. What we have is a number of days of lower demand. What we should do is focus monitoring testing in these days to balance the demand profile, however it may be being held over as surge capacity

DangerScouse · 10-09-2020 09:56AM

drunkmonkey wrote: »

Nobody saving you won't get it but it won't be severe, how sick were the pair of you and did you pass it on to many?

I was very sick. My eldest had some symptoms including loss of taste and temperature. Mother in law also contracted it.

JDD · 10-09-2020 09:57AM

Widdensushi wrote: »

Surely the meat factories have a higher level of immunity now that will limit any spread from them. Need to be thinking where the virus is going, not where it has been, schools are where any excess capacity should be used, starting with the teachers.

That seems to make sense. Though I think regular testing should continue in nursing homes - they're the tinderbox when it comes to infections and I imagine there are still many vulnerable residents who have no immunity.

DangerScouse · 10-09-2020 09:58AM

Sweet.Science wrote: »

Not a hope . Nov/Dec 2020

So you think in two months time.

Fair enough.

What Username Guidelines · 10-09-2020 09:58AM

Someone calling out the tests vs cases announced

https://twitter.com/ConorRiordan2/status/1303978909856337920?s=20

JDD · 10-09-2020 09:58AM

DangerScouse wrote: »

I was very sick. My eldest had some symptoms including loss of taste and temperature. Mother in law also contracted it.

That's interesting. Who was the first with symptoms i.e. do you think you passed it on to your eldest and MIL or did it come from them?

Covid 19 Part XXII-30,360 in ROI(1,781 deaths) 8,035 in NI (568 deaths)(10/09)Read OP

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