St Johns Wort

anxietyguy77

Hey.

I've decided to give this a go.

Anyone know if this is the standard strength/dosage?

Label recommends 1 or 2 tablets. Just a bit put off by the "extra strength" title.

http://www.herbsofgold.com.au/products/product/1560

RubyGirl

Could be wrong but thought these are not available in Ireland to sell.

locum-motion

St. John's Wort is a prescription only medicine in Ireland. It is not safe to use except under the supervision of a doctor.

It's illegal to import medicines into Ireland from outside the state without a license (which as a private individual you won't get).

It's also illegal to obtain medicines via mail order.

My advice: go to the doctor, and discuss your symptoms with them. If appropriate, the doctor will prescribe it for you.

0lddog

OP, are you located in OZ ? ( linkie )

This stuff isnt safe to use and is restricted in ROI except under the supervision of a doctor ( restriction does not apply to many other EU states )

anxietyguy77

RubyGirl wrote: »

Could be wrong but thought these are not available in Ireland to sell.

locum-motion wrote: »

St. John's Wort is a prescription only medicine in Ireland. It is not safe to use except under the supervision of a doctor.

It's illegal to import medicines into Ireland from outside the state without a license (which as a private individual you won't get).

It's also illegal to obtain medicines via mail order.

My advice: go to the doctor, and discuss your symptoms with them. If appropriate, the doctor will prescribe it for you.

0lddog wrote: »

OP, are you located in OZ ? ( linkie )

This stuff isnt safe to use and is restricted in ROI except under the supervision of a doctor ( restriction does not apply to many other EU states )

I'm in Oz.

So judging from the responses, if I was to try it I should go for the lower dose?

Dom from summer bay

The banana republic, the only country in the world to restrict st johns wort, and it was that fat cu*t Brian cowen who did it.

0lddog

Just wait 'till you cant buy grapefruit juice without a script

locum-motion

0lddog wrote: »

Just wait 'till you cant buy grapefruit juice without a script

Although grapefruit juice does have the potential to affect certain medicines (like St. John's Wort), it is very different in two crucial respects.

1. It is a foodstuff.

2. Nobody's trying to use it to treat a serious psychiatric illness instead of seeing the doctor.

Honor3

Hi,

[+] You are allowed to grow St.Johns Wort in Ireland.

Notes:

• - You must use it for your own use.
• - Seeds,Planting & Use of it is LEGAL.
• - Personal Use = LEGAL.

[-] It is just banned on shelves.


Also, if you consider buying the seeds there are many websites, even ebay,amazon,etc;
But if you do buy the seeds, make sure you get good enough quality ones and research the seeds you are buying.

The seeds are cheap,

Also;
St.Johns Wort can be much more effective than Prozac, as certain St.Johns Wort chemical properties also effect dopamine,gaba,etc ; Prozac from my understanding only effect Serotonin and Noradrenaline,

And hey, I have nothing against Prozac, but getting to a doctor is hard enough, plus St.Johns Wort can be more effective as in, some species of St.johns Wort also may target Dopamine & Gaba & some others, while Prozac and some other antidepressants only effect Serotonin and Noradrenaline, .


Other notes:
Different St.John's Wort seeds (species) = different chemical = different effects.


Other notes:
Don't take too much. From my experience, taking too much off it made me angry. So if it says on the box to take 1-2 pills then do what it says, because I tried taking some more and it made me angry. But when I took less I felt much more happy and in the flow .

WARNING:
St.John's Wort is known to interact with certain medications and even medical conditions .

- E.G: If you are currently taking any medications, then do NOT take St.Johns Wort, talk to your doctor.



Pharmacodynamics:

Hyperforin is believed to be the primary active constituent responsible for the antidepressant and anxiolytic properties of the extracts of St. John's wort. It acts as a reuptake inhibitor of monoamines, including serotonin, norepinephrine, dopamine, and of GABA and glutamate, with IC50 values of 0.05-0.10 mcg/ml for all compounds, with the exception of glutamate, which is in the 0.5 mcg/ml range. It appears to exert these effects by activating the transient receptor potential ion channel TRPC6. Activation of TRPC6 induces the entry of sodium and calcium into the cell which causes inhibition of monoamine reuptake. Hyperforin is also thought to be responsible for the induction of the cytochrome P450 enzymes CYP3A4 and CYP2C9 by binding to and activating the pregnane X receptor (PXR).

Mechanism of action:

Hyperforin is believed to be the primary active constituent responsible for the antidepressant and anxiolytic properties of the extracts of St. John's wort. It acts as a reuptake inhibitor of monoamines, including serotonin, norepinephrine, dopamine, and of GABA and glutamate, with IC50 values of 0.05-0.10 mcg/ml for all compounds, with the exception of glutamate, which is in the 0.5 mcg/ml range. It appears to exert these effects by activating the transient receptor potential ion channel TRPC6. Activation of TRPC6 induces the entry of sodium and calcium into the cell which causes inhibition of monoamine reuptake.

http://www.drugbank.ca/drugs/DB01892

[*] If you buying supplements online, you should do your research about quality. Some products are a complete rip off with very little quality, while other products have the highest of quality and are at a excellent price.

WARNING:
- ALWAYS Consult with your doctor before taking St.Johns Wort.

**** - IF YOU HAVE ANY MEDICAL CONDITIONS AND OR YOU ARE TAKING MEDICATIONS THEN YOU MUST TALK TO YOUR DOCTOR FIRST. ST.JOHN'S WORT INTERACTS WITH SOME MEDICATIONS AND CONDITIONS. ****