Hi I am just wondering if there is anyone else who takes difene on a daily basis. I take a minimum of 1 75g difene each day. I have RA and in the past have tried methotrexate and plaquenil and also tried sulphasalazin which made me sick. The combo of methotrexate and plaqunil worked some what but I still had flareups and regularly needed difene to deal with the pain. I stopped these two medicines a couple of years back as I was always sick, at best I always felt as if I was getting a cold at worst I got every bug going. since stopping I feel better in myself I only get 1/2 bugs/colds a year and they are never as bad as before.
However I do worry about the long term effects difene may have on my organs. I know if I stopped taking them my quality of life would suffer and I would strugle to care for my family and working would be out of the question. Any thoughts?